Functional Information from GO Data
Chain | GOid | namespace | contents |
1 | 0004252 | molecular_function | serine-type endopeptidase activity |
1 | 0005576 | cellular_component | extracellular region |
1 | 0006508 | biological_process | proteolysis |
1 | 0007596 | biological_process | blood coagulation |
2 | 0004252 | molecular_function | serine-type endopeptidase activity |
2 | 0005509 | molecular_function | calcium ion binding |
2 | 0006508 | biological_process | proteolysis |
2 | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE IH3 2 370 |
Chain | Residue |
2 | PRO111 |
2 | ARG173 |
2 | ILE174 |
2 | ASP189 |
2 | ALA190 |
2 | SER195 |
2 | VAL213 |
2 | SER214 |
2 | TRP215 |
2 | GLY216 |
2 | GLU217 |
2 | GLY219 |
2 | GLY226 |
2 | PHE227 |
2 | TYR228 |
2 | HOH555 |
2 | HOH573 |
2 | HOH574 |
2 | HOH575 |
2 | HOH584 |
2 | ARG50 |
2 | HIS57 |
2 | TYR60 |
2 | TRP60 |
2 | GLU97 |
2 | LEU99 |
site_id | AC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR CHAIN 3 OF HIRUGEN |
Chain | Residue |
2 | PHE34 |
2 | LEU40 |
2 | ARG67 |
2 | ARG73 |
2 | THR74 |
2 | ARG75 |
2 | TYR76 |
2 | LYS81 |
2 | ILE82 |
2 | MET84 |
2 | THR147 |
2 | TRP148 |
2 | THR149 |
2 | HOH570 |
site_id | CAT |
Number of Residues | 3 |
Details | ACTIVE SITE. |
Chain | Residue |
2 | HIS57 |
2 | ASP102 |
2 | SER195 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
2 | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
Chain | Residue | Details |
2 | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
2 | HIS57 | |
2 | ASP102 | |
2 | SER195 | |
Chain | Residue | Details |
2 | ASN60 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | ASP102 | |
2 | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | SER195 | |
2 | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | SER195 | |
2 | GLY193 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | ASP102 | |
2 | SER195 | |
2 | GLY193 | |
2 | HIS57 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | ASP102 | |
2 | SER195 | |
2 | HIS57 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
2 | ASP102 | |
2 | SER195 | |
2 | HIS57 | |
2 | GLY196 | |