1BOH

SULFUR-SUBSTITUTED RHODANESE (ORTHORHOMBIC FORM)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004792	molecular_function	thiosulfate sulfurtransferase activity
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0008097	molecular_function	5S rRNA binding
A	0016740	molecular_function	transferase activity
A	0016783	molecular_function	sulfurtransferase activity
A	0016784	molecular_function	3-mercaptopyruvate sulfurtransferase activity
A	0035928	biological_process	rRNA import into mitochondrion
A	0051029	biological_process	rRNA transport

Functional Information from PDB Data

site_id	CT1
Number of Residues	5
Details	A CATION (POSSIBLY A NA+ OR A K+) IS PRESENT, IT HAS ESA-COORDINATION.

Chain	Residue
A	GLU71
A	VAL72
A	MET73
A	LYS249
A	ASP272

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Functional Information from PROSITE/UniProt

site_id	PS00380
Number of Residues	12
Details	RHODANESE_1 Rhodanese signature 1. YlerHVPGAsfF

Chain	Residue	Details
A	TYR47-PHE58

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site_id	PS00683
Number of Residues	11
Details	RHODANESE_2 Rhodanese C-terminal signature. VaiYDGSWfEW

Chain	Residue	Details
A	VAL268-TRP278

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Cysteine persulfide intermediate => ECO:0000255|PROSITE-ProRule:PRU00173, ECO:0000269|PubMed:711738

Chain	Residue	Details
A	ARG248

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	TYR187
A	GLY250

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22076378

Chain	Residue	Details
A	TRP14

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P24329

Chain	Residue	Details
A	PRO38

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site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P52196

Chain	Residue	Details
A	GLU136
A	ARG175
A	SER224
A	VAL237

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site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P52196

Chain	Residue	Details
A	THR163
A	LYS236

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site_id	SWS_FT_FI7
Number of Residues	1
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250

Chain	Residue	Details
A	TRP35

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	8
Details	M-CSA 153

Chain	Residue	Details
A	TYR187	electrostatic stabiliser, hydrogen bond donor
A	ARG248	nucleofuge, nucleophile
A	LYS249	electrostatic stabiliser, hydrogen bond donor
A	GLY250	electrostatic stabiliser
A	VAL251	electrostatic stabiliser, hydrogen bond donor
A	THR252	electrostatic stabiliser, hydrogen bond donor
A	ALA253	electrostatic stabiliser, hydrogen bond donor
A	TRP275	electrostatic stabiliser

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