1EED
X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors
Experimental procedure
Spacegroup name | P 1 21 1 |
Unit cell lengths | 43.100, 75.700, 42.900 |
Unit cell angles | 90.00, 96.90, 90.00 |
Refinement procedure
Resolution | 20.000 * - 2.000 |
R-factor | 0.152 * |
Rwork | 0.152 |
RMSD bond length | 0.024 |
RMSD bond angle | 0.029 |
Refinement software | RESTRAIN |
Data quality characteristics
Overall | |
High resolution limit [Å] | 2.000 * |
Rmerge | 0.095 * |
Total number of observations | 88024 * |
Number of reflections | 18024 * |
Completeness [%] | 99.0 * |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | unknown * | Moews, P., (1970) J. Mol. Biol., 54, 395. * |
Crystallization Reagents in Literatures
ID | crystal ID | solution | reagent name | concentration (unit) | details |
1 | 1 | 1 | ammonium sulfate | 2.2 (M) | |
2 | 1 | 1 | acetate | can be replaced with phosphate | |
3 | 1 | 1 | sodium dihydrogen | 0.1 (M) |