2A6E
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-02 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A69
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-02 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A68
| Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-01 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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1TJL
| Crystal structure of transcription factor DksA from E. coli | Descriptor: | DnaK suppressor protein, ZINC ION | Authors: | Perederina, A, Svetlov, V, Vassylyeva, M.N, Artsimovitch, I, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-06-06 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription Cell(Cambridge,Mass.), 118, 2004
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7UWH
| CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex bound to ribonucleotide substrate | Descriptor: | DNA (59-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I. | Deposit date: | 2022-05-03 | Release date: | 2023-05-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | RNA polymerase drives ribonucleotide excision DNA repair in E. coli. Cell, 186, 2023
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7UWE
| CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I. | Deposit date: | 2022-05-03 | Release date: | 2023-05-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | RNA polymerase drives ribonucleotide excision DNA repair in E. coli. Cell, 186, 2023
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2BE5
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-10-22 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12, 2005
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2EUL
| Structure of the transcription factor Gfh1. | Descriptor: | ZINC ION, anti-cleavage anti-GreA transcription factor Gfh1 | Authors: | Symersky, J, Perederina, A, Vassylyeva, M.N, Svetlov, V, Artsimovitch, I, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-10-28 | Release date: | 2005-11-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Regulation through the RNA Polymerase Secondary Channel: STRUCTURAL AND FUNCTIONAL VARIABILITY OF THE COILED-COIL TRANSCRIPTION FACTORS. J.Biol.Chem., 281, 2006
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2OUG
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2P4V
| Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution | Descriptor: | Transcription elongation factor greB | Authors: | Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G. | Deposit date: | 2007-03-13 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors. Embo Rep., 8, 2007
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7U5C
| Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T. | Deposit date: | 2022-03-02 | Release date: | 2022-05-18 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state. Nat.Struct.Mol.Biol., 29, 2022
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6VK1
| CryoEM structure of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK0
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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4WQS
| Thermus thermophilus RNA polymerase backtracked complex | Descriptor: | DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | Deposit date: | 2014-10-22 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.306 Å) | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
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4WQT
| Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | Deposit date: | 2014-10-22 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
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6XAV
| CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | Deposit date: | 2020-06-04 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Pre-termination Transcription Complex: Structure and Function. Mol.Cell, 81, 2021
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6XAS
| CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | Deposit date: | 2020-06-04 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Pre-termination Transcription Complex: Structure and Function. Mol.Cell, 81, 2021
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6CDD
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6CHS
| Cdc48-Npl4 complex in the presence of ATP-gamma-S | Descriptor: | MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. | Deposit date: | 2018-02-22 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
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8SVF
| BAP1/ASXL1 bound to the H2AK119Ub Nucleosome | Descriptor: | DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ... | Authors: | Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J. | Deposit date: | 2023-05-16 | Release date: | 2023-08-30 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Sci Adv, 9, 2023
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7EGS
| The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD | Descriptor: | DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL | Authors: | Zheng, F, Shen, L, Li, L, Zhang, Y. | Deposit date: | 2021-03-26 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crucial role and mechanism of transcription-coupled DNA repair in bacteria. Nature, 604, 2022
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7EGT
| The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB | Descriptor: | DNA helicase UvrD, UvrABC system protein B | Authors: | Zheng, F, Shen, L, Li, L, Zhang, Y. | Deposit date: | 2021-03-26 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.581 Å) | Cite: | Crucial role and mechanism of transcription-coupled DNA repair in bacteria. Nature, 604, 2022
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6VK3
| CryoEM structure of Hrd3/Yos9 complex | Descriptor: | Hrd3, Protein OS-9 homolog | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2020-05-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJZ
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6AWB
| Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state | Descriptor: | 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ... | Authors: | Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. | Deposit date: | 2017-09-05 | Release date: | 2017-10-18 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
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