4V0M
| Crystal structure of BBS1N in complex with ARL6DN | Descriptor: | ARF-LIKE SMALL GTPASE, BARDET-BIEDL SYNDROME 1 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mourao, A, Lorentzen, E. | Deposit date: | 2014-09-17 | Release date: | 2014-11-19 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Structural Basis for Membrane Targeting of the Bbsome by Arl6 Nat.Struct.Mol.Biol., 21, 2014
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2XC7
| Solution Structure of PHAX-RBD in complex with ssRNA | Descriptor: | 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN | Authors: | Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M. | Deposit date: | 2010-04-18 | Release date: | 2010-04-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax. RNA, 16, 2010
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4V0O
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4V0N
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4V0L
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4V0K
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8QF0
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5MF9
| Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide. | Descriptor: | RNA-binding protein 5, Survival motor neuron protein | Authors: | Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J. | Deposit date: | 2016-11-17 | Release date: | 2016-12-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation Elife, 5, 2016
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2W4S
| novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution | Descriptor: | Ankyrin-repeat protein | Authors: | Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S. | Deposit date: | 2008-12-02 | Release date: | 2009-12-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax. RNA, 16, 2010
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5FMS
| mmIFT52 N-terminal domain | Descriptor: | INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG | Authors: | Mourao, A, Lorentzen, E. | Deposit date: | 2015-11-09 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.488 Å) | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex. Embo J., 35, 2016
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5FMR
| crIFT52 N-terminal domain | Descriptor: | INTRAFLAGELLAR TRANSPORT PROTEIN COMPONENT IFT52, SULFATE ION | Authors: | Mourao, A, Vetter, M, Lorentzen, E. | Deposit date: | 2015-11-09 | Release date: | 2016-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex. Embo J., 35, 2016
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5MFY
| RBM5 OCRE domain | Descriptor: | RNA-binding protein 5 | Authors: | Warner, L.R, Mourao, A, Soni, K, Sattler, M. | Deposit date: | 2016-11-19 | Release date: | 2016-12-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation. Elife, 5, 2016
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7NT4
| X-ray structure of SCoV2-PLpro in complex with small molecule inhibitor | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 3, PROFLAVIN, ... | Authors: | Napolitano, V, Mourao, A, Bostock, M, Matsuda, A, Czarna, A, Popowicz, G.M. | Deposit date: | 2021-03-09 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses. Cell Chem Biol, 29, 2022
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8Q8J
| Crystal structure of human GPX4-R152H | Descriptor: | Glutathione peroxidase | Authors: | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | Deposit date: | 2023-08-18 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of human GPX4-R152H To Be Published
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8Q8N
| Crystal structure of human GPX4-U46C-I129S-L130S | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | Authors: | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | Deposit date: | 2023-08-18 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration To Be Published
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2XNF
| The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains | Descriptor: | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | Authors: | Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P. | Deposit date: | 2010-08-02 | Release date: | 2011-03-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain. Nat.Struct.Mol.Biol., 18, 2011
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2WJV
| Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ... | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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2WJY
| Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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5N4A
| Crystal structure of Chlamydomonas IFT80 | Descriptor: | GLYCEROL, Intraflagellar transport protein 80, OXALATE ION | Authors: | Taschner, M, Mourao, A. | Deposit date: | 2017-02-10 | Release date: | 2018-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis. Elife, 7, 2018
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7PO6
| Xist (m6A)UCG tetraloop RNA bound to the YTH domain of YTHDC1 | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, Isoform 2 of YTH domain-containing protein 1, ... | Authors: | Jones, A.N, Mourao, A, Sattler, M. | Deposit date: | 2021-09-08 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1. Nucleic Acids Res., 50, 2022
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5MZH
| Crystal structure of ODA16 from Chlamydomonas reinhardtii | Descriptor: | Dynein assembly factor with WDR repeat domains 1, SULFATE ION | Authors: | Lorentzen, E, Taschner, M, Basquin, J, Mourao, A. | Deposit date: | 2017-01-31 | Release date: | 2017-03-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46. J. Biol. Chem., 292, 2017
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5FMT
| CrIFT54 CH-domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FLAGELLAR ASSOCIATED PROTEIN, GLYCEROL, ... | Authors: | Weber, K, Lorentzen, E. | Deposit date: | 2015-11-09 | Release date: | 2016-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex. Embo J., 35, 2016
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2WAC
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5FMU
| MmIFT54 CH-domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TRAF3-INTERACTING PROTEIN 1 | Authors: | Weber, K, Lorentzen, E. | Deposit date: | 2015-11-09 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.593 Å) | Cite: | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex. Embo J., 35, 2016
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7POF
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