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2XQB
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BU of 2xqb by Molmil
Crystal Structure of anti-IL-15 Antibody in Complex with human IL-15
Descriptor: ANTI-IL-15 ANTIBODY, INTERLEUKIN 15, SULFATE ION
Authors:Lowe, D.C, Gerhardt, S, Ward, A, Hargreaves, D, Anderson, M, StGallay, S, Vousden, K, Ferraro, F, Pauptit, R.A, Cochrane, D, Pattison, D.V, Buchanan, C, Popovic, B, Finch, D.K, Wilkinson, T, Sleeman, M, Vaughan, T.J, Cruwys, S, Mallinder, P.R.
Deposit date:2010-09-01
Release date:2010-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope.
J.Mol.Biol., 406, 2011
4UV4
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BU of 4uv4 by Molmil
Crystal structure of anti-FPR Fpro0165 Fab fragment
Descriptor: FPRO0165 FAB
Authors:Douthwaite, J.A, Sridharan, S, Huntington, C, Marwood, R, Hammersley, J, Hakulinen, J.K, Ek, M, Sjogren, T, Rider, D, Privezentzev, C, Seaman, J.C, Cariuk, P, Knights, V, Young, J, Wilkinson, T, Sleeman, M, Finch, D.K, Lowe, D.C, Vaughan, T.J.
Deposit date:2014-08-04
Release date:2014-12-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1.
Mabs, 7, 2015
6I8S
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BU of 6i8s by Molmil
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1
Descriptor: HEAVY CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, LIGHT CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, Plasminogen activator inhibitor 1
Authors:Vousden, K.A, Lundqvist, T, Popovic, B.
Deposit date:2018-11-21
Release date:2019-02-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Sci Rep, 9, 2019
5JZ7
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BU of 5jz7 by Molmil
NGF IN COMPLEX WITH MEDI578 scFv
Descriptor: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ...
Authors:Olsson, L.-L, Aagaard, A.
Deposit date:2016-05-16
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
1BBJ
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BU of 1bbj by Molmil
CRYSTAL STRUCTURE OF A CHIMERIC FAB' FRAGMENT OF AN ANTIBODY BINDING TUMOUR CELLS
Descriptor: IGG4-KAPPA B72.3 FAB (HEAVY CHAIN), IGG4-KAPPA B72.3 FAB (LIGHT CHAIN)
Authors:Brady, R.L, Hubbard, R.E, Todd, R.J.
Deposit date:1992-04-30
Release date:1994-01-31
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells.
J.Mol.Biol., 227, 1992

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