6QEY
| IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties | Descriptor: | ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION | Authors: | Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A. | Deposit date: | 2019-01-09 | Release date: | 2019-03-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties. Nucleic Acids Res., 47, 2019
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2LFG
| Solution structure of the human prolactin receptor ecd domain d2 | Descriptor: | Prolactin receptor | Authors: | Dagil, R, Knudsen, M.J, Kragelund, B.B, O'Shea, C, Teilum, K. | Deposit date: | 2011-06-30 | Release date: | 2012-02-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor Structure, 20, 2012
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2M0P
| Solution structure of the tenth complement type repeat of human megalin | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor-related protein 2 | Authors: | Dagil, R, Kragelund, B. | Deposit date: | 2012-11-01 | Release date: | 2013-01-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin. J.Biol.Chem., 288, 2013
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7B52
| VAR2CSA full ectodomain | Descriptor: | Erythrocyte membrane protein 1 | Authors: | Wang, K.T, Gourdon, P.E, Dagil, R, Salanti, A. | Deposit date: | 2020-12-03 | Release date: | 2021-04-21 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021
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7B54
| VAR2CSA full ectodomain in present of plCS, DBL1-DBL4 | Descriptor: | VAR2CSA in presence of plCS, DBl1-DBL4,Erythrocyte membrane protein 1 | Authors: | Wang, K.T, Dagil, R, Gourdon, P.E, Salanti, A. | Deposit date: | 2020-12-03 | Release date: | 2021-06-02 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021
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8P2E
| Homotypic interacting B1 fab bound to Chondroitin Sulfate A | Descriptor: | B1 fab heavy, B1 fab light | Authors: | Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A. | Deposit date: | 2023-05-16 | Release date: | 2024-06-05 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate. Nat Commun, 15, 2024
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7NNH
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2UZJ
| Crystal structure of the mature streptococcal cysteine protease, mSpeB | Descriptor: | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, STREPTOPAIN | Authors: | Olsen, J.G, Dagil, R, Niclasen, L.M, Soerensen, O.E, Kragelund, B.B. | Deposit date: | 2008-09-16 | Release date: | 2009-09-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of the Mature Streptococcal Cysteine Protease Exotoxin Mspeb in its Active Dimeric Form. J.Mol.Biol., 393, 2009
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7Z1H
| VAR2CSA APO | Descriptor: | VAR2CSA APO | Authors: | Raghavan, S.S.R, Wang, K.T. | Deposit date: | 2022-02-24 | Release date: | 2022-11-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA. Plos Pathog., 18, 2022
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7Z12
| VAR2 complex with PAM1.4 | Descriptor: | PAM1.4, Heavy Chain, light Chain, ... | Authors: | Raghavan, S.S.R, Wang, K.T. | Deposit date: | 2022-02-24 | Release date: | 2022-11-02 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA. Plos Pathog., 18, 2022
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