1GVN
| Crystal Structure of the Plasmid Maintenance System epsilon/zeta: Meachnism of toxin inactivation and toxin function | Descriptor: | EPSILON, SULFATE ION, ZETA | Authors: | Meinhart, A, Alonso, J.C, Straeter, N, Saenger, W. | Deposit date: | 2002-02-19 | Release date: | 2003-01-29 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation Proc.Natl.Acad.Sci.USA, 100, 2003
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1Q1H
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1SZA
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1SZ9
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6QDJ
| Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | Descriptor: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Meinhart, A, Clausen, T, Arnese, R. | Deposit date: | 2019-01-02 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin. Nat Commun, 10, 2019
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6QDL
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6ZK7
| Crystal Structure of human PYROXD1/FAD complex | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | Authors: | Meinhart, A, Asanovic, I, Martinez, J, Clausen, T. | Deposit date: | 2020-06-30 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Mol.Cell, 81, 2021
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7AA4
| Structure of ClpC1-NTD bound to a CymA analogue | Descriptor: | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue | Authors: | Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. | Deposit date: | 2020-09-03 | Release date: | 2021-08-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
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6QDM
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6QDK
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8B9U
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8B9O
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7BII
| Crystal structure of Nematocida HUWE1 | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | Authors: | Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T. | Deposit date: | 2021-01-12 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.037 Å) | Cite: | HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nat.Chem.Biol., 17, 2021
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6TV6
| Octameric McsB from Bacillus subtilis. | Descriptor: | MAGNESIUM ION, Protein-arginine kinase | Authors: | Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T. | Deposit date: | 2020-01-09 | Release date: | 2021-07-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. Elife, 10, 2021
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7OYC
| Cryo-EM structure of the Xenopus egg 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-20 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYD
| Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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4XW3
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5FGT
| Thaumatin solved by native sulphur-SAD using free-electron laser radiation | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Nass, K.J, Meinhart, A, Barends, T.R.M, Foucar, L, Gorel, A, Aquila, A, Botha, S, Doak, R.B, Koglin, J, Liang, M, Shoeman, R.L, Williams, G.K, Boutet, S, Schlichting, I. | Deposit date: | 2015-12-21 | Release date: | 2016-06-08 | Last modified: | 2018-11-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein structure determination by single-wavelength anomalous diffraction phasing of X-ray free-electron laser data. Iucrj, 3, 2016
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5FGX
| Thaumatin solved by native sulphur SAD using synchrotron radiation | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Nass, K.J, Meinhart, A, Barends, T.R.M, Foucar, L, Gorel, A, Aquila, A, Botha, S, Doak, R.B, Koglin, J, Liang, M, Shoeman, R.L, Williams, G.J, Boutet, S, Schlichting, I. | Deposit date: | 2015-12-21 | Release date: | 2016-06-08 | Method: | X-RAY DIFFRACTION (2.134 Å) | Cite: | Protein structure determination by single-wavelength anomalous diffraction phasing of X-ray free-electron laser data. Iucrj, 3, 2016
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3ISM
| Crystal structure of the EndoG/EndoGI complex: Mechanism of EndoG inhibition | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CG4930, CG8862, ... | Authors: | Loll, B, Gebhardt, M, Wahle, E, Meinhart, A. | Deposit date: | 2009-08-26 | Release date: | 2009-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition. Nucleic Acids Res., 37, 2009
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7OYB
| Cryo-EM structure of the 6 hpf zebrafish embryo 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYA
| Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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2P5T
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7QVE
| Spinach 20S proteasome | Descriptor: | Proteasome subunit alpha type, Proteasome subunit alpha type-3, Proteasome subunit beta, ... | Authors: | Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. | Deposit date: | 2022-01-21 | Release date: | 2022-05-25 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the plant 26S proteasome. Plant Commun., 3, 2022
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7ABR
| Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ... | Authors: | Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T. | Deposit date: | 2020-09-08 | Release date: | 2021-10-06 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
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