7OYC

Cryo-EM structure of the Xenopus egg 80S ribosome

This is a non-PDB format compatible entry.

Summary for 7OYC

• Entry DOI: 10.2210/pdb7oyc/pdb
• EMDB information: 13113
• Descriptor: Eukaryotic translation initiation factor 5A, 60S ribosomal protein L4-B, 40S ribosomal protein S2, ... (83 entities in total)
• Functional Keywords: eif5a, eef2, habp4, dapl1, dap1, egg, xenopus, ribosome
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 81
• Total formula weight: 3587980.74

Authors

Leesch, F.,Lorenzo-Orts, L.,Grishkovskaya, I.,Kandolf, S.,Belacic, K.,Meinhart, A.,Haselbach, D.,Pauli, A. (deposition date: 2021-06-24, release date: 2022-07-20, Last modification date: 2023-02-08)

• Primary citation: Leesch, F.,Lorenzo-Orts, L.,Pribitzer, C.,Grishkovskaya, I.,Roehsner, J.,Chugunova, A.,Matzinger, M.,Roitinger, E.,Belacic, K.,Kandolf, S.,Lin, T.Y.,Mechtler, K.,Meinhart, A.,Haselbach, D.,Pauli, A.; A molecular network of conserved factors keeps ribosomes dormant in the egg.; Nature, 613:712-720, 2023; PubMed: 36653451; DOI: 10.1038/s41586-022-05623-y

Experimental method

ELECTRON MICROSCOPY (2.4 Å)