PDB: 159 resultsInfo pagesStatus searchChemie searchBIRD

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6ZD9	Crystal structure of YTHDC1 apo purified using GST tag Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTHDC1 Authors: Bedi, R.K, Caflisch, A. Deposit date: 2020-06-14 Release date: 2020-07-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
6ZCN	Crystal structure of YTHDC1 with m6A Descriptor: N6-METHYLADENOSINE-5'-MONOPHOSPHATE, SULFATE ION, YTHDC1 Authors: Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A. Deposit date: 2020-06-11 Release date: 2020-07-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
6ZCM	Crystal structure of YTHDC1 with compound DHU_DC1_180 Descriptor: 6-[[cyclopropyl-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]amino]methyl]-1~{H}-pyrimidine-2,4-dione, SULFATE ION, YTHDC1 Authors: Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A. Deposit date: 2020-06-11 Release date: 2020-07-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
8Q2Q	Crystal structure of YTHDC1 in complex with Compound 2b (YL_32) Descriptor: 2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Li, Y, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 2b (YL_32) To Be Published
8Q4W	Crystal structure of YTHDC1 in complex with Compound 40 (CS_3a) Descriptor: 5-chloranyl-3-[(3-chlorophenyl)methyl]-~{N}-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 40 (CS_3a) To Be Published
8Q2X	Crystal structure of YTHDC1 in complex with Compound 10 (ZA_294) Descriptor: 3-[2-chloranyl-6-(methylamino)purin-9-yl]benzoic acid, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 10 (ZA_294) To Be Published
8Q4U	Crystal structure of YTHDC1 in complex with Compound 36 (ZA_540b) Descriptor: 9-[(3-chlorophenyl)methyl]-2-fluoranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 36 (ZA_540b) To Be Published
8Q31	Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341) Descriptor: 9-[(2-aminophenyl)methyl]-2-chloranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341) To Be Published
8Q4V	Crystal structure of YTHDC1 in complex with Compound 37 (ZA_356) Descriptor: 2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-cyclopropyl-7,8-dihydropurin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 37 (ZA_356) To Be Published
8Q32	Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364) Descriptor: SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364) To Be Published
8Q2S	Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232) Descriptor: 2-chloranyl-~{N}-methyl-9-phenyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232) To Be Published
8Q2T	Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236) Descriptor: 2-chloranyl-~{N}-methyl-9-(phenylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236) To Be Published
8Q2W	Crystal structure of YTHDC1 in complex with Compound 8 (CS_01) Descriptor: 2-chloranyl-9-(cyclohexylmethyl)-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 8 (CS_01) To Be Published
8Q38	Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347) Descriptor: SULFATE ION, YTH domain-containing protein 1, methyl 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoate Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347) To Be Published
8Q2U	Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308) Descriptor: 2-chloranyl-~{N}-methyl-9-(pyridin-4-ylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308) To Be Published
8Q4P	Crystal structure of YTHDC1 in complex with Compound 27 (ZA_309) Descriptor: 2-chloranyl-9-[(3-methoxyphenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 27 (ZA_309) To Be Published
8Q4T	Crystal structure of YTHDC1 in complex with Compound 31 (ZA_400) Descriptor: SULFATE ION, YTH domain-containing protein 1, ~{N}-[4-chloranyl-2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 31 (ZA_400) To Be Published
8Q2V	Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560) Descriptor: 2-chloranyl-~{N}-methyl-9-[(2~{S})-oxan-2-yl]purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560) To Be Published
8Q4N	Crystal structure of YTHDC1 in complex with Compound 26 (ZA_513) Descriptor: 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzenecarbonitrile, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 26 (ZA_513) To Be Published
8Q2Y	Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572) Descriptor: 2-[2-chloranyl-6-(methylamino)purin-9-yl]-~{N}-phenyl-ethanamide, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572) To Be Published
8Q3A	Crystal structure of YTHDC1 in complex with Compound 22 (ZA_393) Descriptor: 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzamide, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 22 (ZA_393) To Be Published
8Q37	Crystal structure of YTHDC1 in complex with Compound 18 (ZA_312) Descriptor: 2-chloranyl-9-[(2-methoxyphenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 18 (ZA_312) To Be Published
8Q33	Crystal structure of YTHDC1 in complex with Compound 15 (ZA_343) Descriptor: SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]-2,2,2-tris(fluoranyl)ethanamide Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-03 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 15 (ZA_343) To Be Published
8Q4M	Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349) Descriptor: 2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349) To Be Published
8Q4R	Crystal structure of YTHDC1 in complex with Compound 30 (ZA_326) Descriptor: SULFATE ION, YTH domain-containing protein 1, [4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanol Authors: Bedi, R.K, Zalesak, F, Caflisch, A. Deposit date: 2023-08-07 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of YTHDC1 in complex with Compound 30 (ZA_326) To Be Published

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