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4FPO	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-chloro-4-methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-chloro-4-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.591 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-ammoniopropane-1-sulfonate Descriptor: 3-aminopropane-1-sulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FP3	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(Furan-2-ylmethyl)ammonio]sulfonate Descriptor: 2-[(furan-2-ylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.743 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPJ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-bromobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-23 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOQ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-aminoethanesulfonic acid Descriptor: 2-AMINOETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-(Benzylammonio)ethanesulfonate Descriptor: 2-(benzylamino)ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPH	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Fluorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-fluorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.938 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FOV	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPC	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-chlorobenzyl)amino]ethanesulfonic acid, GLYCEROL, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FQ4	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Fluoro-3-methylbenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-fluoro-3-methylbenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-25 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPK	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-methylbenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methylbenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPF	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-chlorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FP2	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2[(Cyclohexylmethyl)ammonio]sulfonate Descriptor: 2-[(cyclohexylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPL	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3,4-dichlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3,4-dichlorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPE	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.181 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPG	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Hydroxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-hydroxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.576 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4XJ8	Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 5.0 in 50mM sodium Acetate with DMSO Descriptor: Sialidase B Authors: Brear, P. Deposit date: 2015-01-08 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.749 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XE9	Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2014-12-23 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.84 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XHB	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES Descriptor: (1R,2S)-cyclopentane-1,2-diol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sialidase B Authors: Brear, P. Deposit date: 2015-01-05 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.88 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJW	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... Authors: Brear, P. Deposit date: 2015-01-09 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.53 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XOG	CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH Optactin and DANA Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, DIMETHYL SULFOXIDE, ... Authors: Brear, P. Deposit date: 2015-01-16 Release date: 2016-02-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJ9	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 5.0 in 50mM Sodium Acetate with DMSO as the cryoprotectant Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2015-01-08 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.98 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XJZ	Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 7.4 in PBS with DMSO Descriptor: DIMETHYL SULFOXIDE, PHOSPHATE ION, Sialidase B Authors: Brear, P. Deposit date: 2015-01-09 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.56 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XIO	Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectant Descriptor: Sialidase B Authors: Brear, P. Deposit date: 2015-01-07 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published

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