PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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5W8J	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 分子名称: 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Lukacs, C.M, Moulin, A. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
5W8K	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 and NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ... 著者 Lukacs, C.M, Dranow, D.M. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
3PQE	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation 分子名称: L-lactate dehydrogenase 著者 Zhang, Y, Garavito, R.M. 登録日 2010-11-26 公開日 2011-12-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation To be Published
3PQF	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+ 分子名称: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Zhang, Y, Garavito, R.M. 登録日 2010-11-26 公開日 2012-01-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+ To be Published
5W8I	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 23 and Zinc 分子名称: 2-[3-(3,4-difluorophenyl)-5-hydroxy-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, CITRIC ACID, DIMETHYL SULFOXIDE, ... 著者 Lukacs, C.M, Abendroth, J. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
5W8L	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 59 and NADH 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-([1,1'-biphenyl]-3-yl)-5-(cyclopropylmethyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, ... 著者 Davies, D.R, Dranow, D.M. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
3PQD	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+ 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Zhang, Y, Garavito, R.M. 登録日 2010-11-26 公開日 2012-01-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.376 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+ To be Published
5W8H	Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 11 分子名称: 2-[3-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Lukacs, C.M, Dranow, D.M. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
1GUZ	Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases 分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dalhus, B, Sarinen, M, Sauer, U.H, Eklund, P, Johansson, K, Karlsson, A, Ramaswamy, S, Bjork, A, Synstad, B, Naterstad, K, Sirevag, R, Eklund, H. 登録日 2002-02-04 公開日 2002-02-21 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases J.Mol.Biol., 318, 2002
1SEV	Mature and translocatable forms of glyoxysomal malate dehydrogenase have different activities and stabilities but similar crystal structures 分子名称: Malate dehydrogenase, glyoxysomal precursor 著者 Cox, B.R, Chit, M.M, Weaver, T.M, Bailey, J, Gietl, C, Bell, E, Banaszak, L.J. 登録日 2004-02-18 公開日 2005-01-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Organelle and translocatable forms of glyoxysomal malate dehydrogenase. The effect of the N-terminal presequence Febs J., 272, 2005
4UUL	Apo trichomonas vaginalis lactate dehydrogenase L91R 分子名称: L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, L Theobald, D. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
7AOB	Crystal structure of Thermaerobacter marianensis malate dehydrogenase 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Bertrand, Q, Lasalle, L, Girard, E, Madern, D. 登録日 2020-10-14 公開日 2020-10-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal structure of Thermaerobacter marianensis malate dehydrogenase To Be Published
4UUM	Apo trichomonas vaginalis lactate dehydrogenase 分子名称: L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.368 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4UUN	Trichomonas vaginalis lactate dehydrogenase in complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4UUO	Apo Trichomonas vaginalis malate dehydrogenase 分子名称: CYTOSOLIC MALATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2016-07-06 実験手法 X-RAY DIFFRACTION (2.842 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4WLF	Crystal structure of L-malate bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-malate bound MDH2 To Be Published
4WLN	Crystal structure of apo MDH2 分子名称: Malate dehydrogenase, mitochondrial, PHOSPHATE ION 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of apo MDH2 To Be Published
4WLE	Crystal structure of citrate bound MDH2 分子名称: CITRIC ACID, Malate dehydrogenase, mitochondrial 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of citrate bound MDH2 To Be Published
2FN7	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: GLYCEROL, LACTIC ACID, Lactate Dehydrogenase, ... 著者 Senkovich, O.A, Chattopadhyay, D. 登録日 2006-01-10 公開日 2007-01-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of cryptosporidium parvum lactate dehydrogenase in complex with substrates and cofactors To be Published
4WLV	Crystal structure of NAD bound MDH2 分子名称: Malate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-08 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of NAD bound MDH2 To Be Published
7BYA	Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Adenosine 5'-Diphosphoribose (APR) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Malate dehydrogenase, OXALOACETATE ION 著者 Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. 登録日 2020-04-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus. J.Biochem., 170, 2021
7BY9	Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Nicotinamide Adenine Dinucleotide (NAD) 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION 著者 Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. 登録日 2020-04-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus. J.Biochem., 170, 2021
7BY8	Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) 分子名称: Malate dehydrogenase 著者 Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. 登録日 2020-04-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.945 Å) 主引用文献 Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus. J.Biochem., 170, 2021
2A92	Crystal structure of lactate dehydrogenase from Plasmodium vivax: complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase 著者 Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. 登録日 2005-07-11 公開日 2006-01-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH. Biochemistry, 44, 2005
2A94	Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH. 分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase 著者 Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. 登録日 2005-07-11 公開日 2006-01-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH. Biochemistry, 44, 2005

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