5EMY
| Human Pancreatic Alpha-Amylase in complex with the mechanism based inactivator glucosyl epi-cyclophellitol | 分子名称: | (1R,2R,3S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)cyclohexyl alpha-D-glucopyranoside, CALCIUM ION, CHLORIDE ION, ... | 著者 | Caner, S, Brayer, G.D. | 登録日 | 2015-11-06 | 公開日 | 2016-07-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.231 Å) | 主引用文献 | Glucosyl epi-cyclophellitol allows mechanism-based inactivation and structural analysis of human pancreatic alpha-amylase. Febs Lett., 590, 2016
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5GR0
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5GQU
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5GR6
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5GR3
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5GQV
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5GR4
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5GQY
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5GR1
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5GR2
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5GR5
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5GQX
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5GQW
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5GQZ
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1JFH
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1JD7
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1JXK
| Role of ethe mobile loop in the mehanism of human salivary amylase | 分子名称: | Alpha-amylase, salivary, CALCIUM ION, ... | 著者 | Ramasubbu, N, Ragunath, C, Wang, Z. | 登録日 | 2001-09-07 | 公開日 | 2001-09-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase J.Mol.Biol., 325, 2003
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1JXJ
| Role of mobile loop in the mechanism of human salivary amylase | 分子名称: | Alpha-amylase, salivary, CALCIUM ION, ... | 著者 | Ramasubbu, N, Ragunath, C, Wang, Z, Mishra, P.J, Thomas, L.M. | 登録日 | 2001-09-07 | 公開日 | 2001-09-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity. Eur.J.Biochem., 271, 2004
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1KB3
| Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-05 | 公開日 | 2002-05-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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1KBK
| Mechanistic Analyses of Catalysis in Human Pancreatic Alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-06 | 公開日 | 2002-04-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41, 2002
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1KCK
| Bacillus circulans strain 251 Cyclodextrin glycosyl transferase mutant N193G | 分子名称: | 1-AMINO-2,3-DIHYDROXY-5-HYDROXYMETHYL CYCLOHEX-5-ENE, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ... | 著者 | Rozeboom, H.J, Uitdehaag, J.C.M, Dijkstra, B.W. | 登録日 | 2001-11-09 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism. J.Biol.Chem., 277, 2002
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1KCL
| Bacillus ciruclans strain 251 Cyclodextrin glycosyl transferase mutant G179L | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cyclodextrin glycosyltransferase, ... | 著者 | Rozeboom, H.J, Uitdehaag, J.C.M, Dijkstra, B.W. | 登録日 | 2001-11-09 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism. J.Biol.Chem., 277, 2002
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1KBB
| Mechanistic Analyses of Catalysis in Human Pancreatic alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-05 | 公開日 | 2002-04-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41, 2002
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1KXH
| Crystal structure of the complex between an inactive mutant of psychrophilic alpha-amylase (D174N) and acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Aghajari, N, Haser, R. | 登録日 | 2002-01-31 | 公開日 | 2002-06-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase. Biochemistry, 41
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1KXT
| Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | 著者 | Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C. | 登録日 | 2002-02-01 | 公開日 | 2002-06-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology. J.Biol.Chem., 277, 2002
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