PDB: 322 件ウェブページステータス検索Chemie searchBIRD

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8PBI	Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate 分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 del Cano-Ochoa, F, Ramon-Maiques, S. 登録日 2023-06-09 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBJ	Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate 分子名称: CAD protein, FORMIC ACID, GLYCEROL, ... 著者 del Cano-Ochoa, F, Ramon-Maiques, S. 登録日 2023-06-09 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBH	Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate 分子名称: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... 著者 del Cano-Ochoa, F, Ramon-Maiques, S. 登録日 2023-06-09 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
1GKP	D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HYDANTOINASE, SULFATE ION, ... 著者 Abendroth, J, Niefind, K, Schomburg, D. 登録日 2001-08-20 公開日 2002-06-27 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (1.295 Å) 主引用文献 X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
1GKR	L-Hydantoinase (Dihydropyrimidinase) from Arthrobacter aurescens 分子名称: NON-ATP DEPENDENT L-SELECTIVE HYDANTOINASE, ZINC ION 著者 Abendroth, J, Niefind, K, Schomburg, D. 登録日 2001-08-20 公開日 2002-07-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structure of L-hydantoinase from Arthobacter aurescens leads to an understanding of dihydropyrimidinase substrate and enantio specificity. Biochemistry, 41, 2002
1GKQ	D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group P212121 分子名称: HYDANTOINASE, ZINC ION 著者 Abendroth, J, Niefind, K, Schomburg, D. 登録日 2001-08-20 公開日 2002-06-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
1J79	Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear Metal Center 分子名称: N-CARBAMOYL-L-ASPARTATE, OROTIC ACID, ZINC ION, ... 著者 Thoden, J.B, Phillips Jr, G.N, Neal, T.M, Raushel, F.M, Holden, H.M. 登録日 2001-05-16 公開日 2001-06-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear metal center. Biochemistry, 40, 2001
1J6P	Crystal structure of Metal-dependent hydrolase of cytosinedemaniase/chlorohydrolase family (TM0936) from Thermotoga maritima at 1.9 A resolution 分子名称: METAL-DEPENDENT HYDROLASE OF CYTOSINEDEMANIASE/CHLOROHYDROLASE FAMILY, NICKEL (II) ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2002-07-09 公開日 2002-10-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Metal-dependent hydrolase of cytosinedemaniase/chlorohydrolase family (TM0936) from Thermotoga maritima at 1.9 A resolution To be published
6GDD	DIHYDROOROTASE FROM AQUIFEX AEOLICUS UNDER 1200 BAR OF HYDROSTATIC PRESSURE 分子名称: Dihydroorotase, SULFATE ION, ZINC ION 著者 Prange, T, Girard, E, Herve, G, Evans, D.R. 登録日 2018-04-23 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Pressure-induced activation of latent dihydroorotase from Aquifex aeolicus as revealed by high pressure protein crystallography. Febs J., 286, 2019
6FV4	The structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D267A mutant from Mycobacterium smegmatis in complex with N-acetyl-D-glucosamine-6-phosphate 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, CADMIUM ION, ... 著者 Ahangar, M.S, Furze, C.M, Guy, C.S, Cooper, C, Maskew, K.S, Graham, B, Cameron, A.D, Fullam, E. 登録日 2018-03-01 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.974 Å) 主引用文献 Structural and functional determination of homologs of theMycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA). J. Biol. Chem., 293, 2018
6GDF	DIHYDROOROTASE FROM AQUIFEX AEOLICUS UNDER 600 BAR OF HYDROSTATIC PRESSURE 分子名称: Dihydroorotase, SULFATE ION, ZINC ION 著者 Prange, T, Girard, E, Herve, G, Evans, D.R. 登録日 2018-04-23 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pressure-induced activation of latent dihydroorotase from Aquifex aeolicus as revealed by high pressure protein crystallography. Febs J., 286, 2019
6HFD	Human dihydroorotase mutant F1563L apo structure 分子名称: CAD protein, FORMIC ACID, ZINC ION 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.869968 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFK	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.459144 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFL	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG1	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state 分子名称: CAD protein,Dihydroorotase,CAD protein, FORMIC ACID, ZINC ION 著者 Ramon-Maiques, S, Del Cano-Ochoa, F. 登録日 2018-08-22 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFF	Human dihydroorotase mutant F1563Y apo structure 分子名称: CAD protein, FORMIC ACID, ZINC ION 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.51000106 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFQ	Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.1454246 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFE	Human dihydroorotase mutant F1563T apo structure 分子名称: CAD protein, FORMIC ACID, ZINC ION 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.47997439 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFU	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5 分子名称: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3997103 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFN	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.44965148 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFP	Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.1982286 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG3	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Del Cano-Ochoa, F. 登録日 2018-08-22 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFH	Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.44871271 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFR	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0 分子名称: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.29949379 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG2	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to fluoroorotate 分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Del Cano-Ochoa, F. 登録日 2018-08-22 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

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