PDB: 121 件ウェブページステータス検索Chemie searchBIRD

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6E2W	MDDEF in complex with MVAPP, ADP, sulfate and cobalt 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2018-07-12 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
6E2V	MDDEF in complex with MVAPP, ADPBeF3 and magnesium 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2018-07-12 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
6E2Y	MDDEF in complex with MVAPP, ADP, sulfate and cobalt. Anomalous data 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2018-07-12 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
6QJE	Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 4-[(2-methylsulfonylimidazol-1-yl)methyl]-1,3-thiazole, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2019-01-24 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole To Be Published
2HKE	Mevalonate diphosphate decarboxylase from Trypanosoma brucei 分子名称: Diphosphomevalonate decarboxylase, putative, SULFATE ION 著者 Byres, E, Alphey, M.S, Hunter, W.N. 登録日 2006-07-04 公開日 2007-06-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity J.Mol.Biol., 371, 2007
6Q90	Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-16 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea To Be Published
2HK2	Crystal structure of mevalonate diphosphate decarboxylase from Staphylococcus aureus (monoclinic form) 分子名称: Diphosphomevalonate decarboxylase 著者 Byres, E, Hunter, W.N. 登録日 2006-07-03 公開日 2007-06-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity J.Mol.Biol., 371, 2007
2HK3	Crystal structure of mevalonate diphosphate decarboxylase from Staphylococcus aureus (orthorhombic form) 分子名称: Diphosphomevalonate decarboxylase 著者 Byres, E, Hunter, W.N. 登録日 2006-07-03 公開日 2007-06-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity J.Mol.Biol., 371, 2007
2HFU	Crystal structure of L. major mevalonate kinase in complex with R-mevalonate 分子名称: (R)-MEVALONATE, Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
2HFS	Crystal structure of L. major mevalonate kinase 分子名称: Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
6MDF	Mevalonate kinase from Methanosarcina mazei with 5-phosphomevalonate bound 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, GLYCEROL, Mevalonate kinase 著者 Miller, B.R, Kung, Y. 登録日 2018-09-04 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE, 13, 2018
2DEI	Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PNP and galactose 分子名称: MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Probable galactokinase, alpha-D-galactopyranose 著者 Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-02-10 公開日 2007-05-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of galaktokinase from Pyrococcus horikoshii To be Published
6ZH0	Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(3-chlorophenyl)-2,2,2-trifluoroacetamide, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2022-06-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
6ZGW	Structure of human galactokinase 1 bound with (4-chlorophenyl)methyl pyridine-3-carboxylate 分子名称: (4-chlorophenyl)methyl pyridine-3-carboxylate, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
6ZGV	Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 2-(4-chlorophenyl)-~{N}-pyrimidin-2-yl-ethanamide, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
6N10	Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
6N0Z	Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase N20K H194M mutant complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
2A2D	X-ray structure of human n-acetyl galactosamine kinase complexed with Mn-AMPPNP and n-acetyl glactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, N-acetylgalactosamine kinase, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
6E2S	apo form of MDDEF with buffer exchange 分子名称: Mevalonate diphosphate decarboxylase, SULFATE ION 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2018-07-12 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.791 Å) 主引用文献 Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
6MDE	Mevalonate kinase from Methanosarcina mazei with mevalonate bound 分子名称: (R)-MEVALONATE, GLYCEROL, Mevalonate kinase, ... 著者 Miller, B.R, Kung, Y. 登録日 2018-09-04 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE, 13, 2018
6N0X	Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase complexed with (R)-MVAP 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, Diphosphomevalonate decarboxylase 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
2AJ4	Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP 分子名称: CHLORIDE ION, Galactokinase, MAGNESIUM ION, ... 著者 Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2005-08-01 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer J.Biol.Chem., 280, 2005
6N0Y	Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
2GS8	Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, mevalonate pyrophosphate decarboxylase 著者 Cuff, M.E, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-04-25 公開日 2006-06-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes To be Published
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005

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