PDB: 56 件ウェブページステータス検索Chemie searchBIRD

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7O9Z	Crystal structure of Human Menin in complex with BD-08 分子名称: (~{E})-2-cyano-3-(2~{H}-indazol-6-yl)-~{N}-(2-morpholin-4-ylethyl)prop-2-enamide, 1,2-ETHANEDIOL, GLYCEROL, ... 著者 Groves, M.R, Gao, K. 登録日 2021-04-18 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Crystal structure of Human Menin in complex with BD-08 To Be Published
2M0G	Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition 分子名称: Splicing factor 1, Splicing factor U2AF 65 kDa subunit 著者 Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. 登録日 2012-10-25 公開日 2013-01-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition. Nucleic Acids Res., 41, 2013
2M09	Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition 分子名称: Splicing factor 1 著者 Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. 登録日 2012-10-22 公開日 2013-01-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition. Nucleic Acids Res., 41, 2013
6BXY	Menin in complex with MI-1481 分子名称: 1,2-ETHANEDIOL, 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, ... 著者 Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. 登録日 2017-12-19 公開日 2018-11-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. J.Med.Chem., 61, 2018
4FXX	Structure of SF1 coiled-coil domain 分子名称: IMIDAZOLE, MALONATE ION, Splicing factor 1 著者 Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. 登録日 2012-07-03 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4801 Å) 主引用文献 Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
4FXW	Structure of phosphorylated SF1 complex with U2AF65-UHM domain 分子名称: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit 著者 Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. 登録日 2012-07-03 公開日 2013-01-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013

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