PDB: 1008 件ウェブページステータス検索Chemie searchBIRD

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5HZ8	FABP4_3 in complex with 6,8-Dichloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid 分子名称: 6,8-dichloro-4-phenyl-2-(piperidin-1-yl)quinoline-3-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... 著者 Ehler, A, Rudolph, M.G. 登録日 2016-02-02 公開日 2016-12-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors. Bioorg. Med. Chem. Lett., 26, 2016
5HZ9	human FABP3 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid 分子名称: 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, CHLORIDE ION, Fatty acid-binding protein, ... 著者 Ehler, A, Rudolph, M.G. 登録日 2016-02-02 公開日 2016-12-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors. Bioorg. Med. Chem. Lett., 26, 2016
5HTD	Recombinant bovine beta-lactoglobulin variant L1A/I2S with endogenous ligand (sBlgB#1) 分子名称: Beta-lactoglobulin, MYRISTIC ACID 著者 Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. 登録日 2016-01-26 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016
5HTE	Recombinant bovine beta-lactoglobulin variant L1A/I2S (sBlgB#2) 分子名称: Beta-lactoglobulin 著者 Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. 登録日 2016-01-26 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016
5B29	The 1.28A structure of human FABP3 F16V mutant complexed with palmitic acid at room temperature 分子名称: Fatty acid-binding protein, heart, PALMITIC ACID 著者 Matsuoka, D, Sugiyama, S, Kakinouchi, K, Niiyama, M, Murata, M, Matsuoka, S. 登録日 2016-01-12 公開日 2017-01-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 The 1.28A structure of human FABP3 F16V mutant complexed with palmitic acid at room temperature. To Be Published
5B27	The 1.02A structure of human FABP3 M20S mutant complexed with palmitic acid 分子名称: Fatty acid-binding protein, heart, PALMITIC ACID, ... 著者 Matsuoka, D, Sugiyama, S, Kakinouchi, K, Niiyama, M, Murata, M, Matsuoka, S. 登録日 2016-01-12 公開日 2017-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 The 1.02A structure of human FABP3 M20S mutant complexed with palmitic acid. To Be Published
5B28	The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid 分子名称: Fatty acid-binding protein, heart, PALMITIC ACID, ... 著者 Matsuoka, D, Sugiyama, S, Kakinouchi, K, Niiyama, M, Murata, M, Matsuoka, S. 登録日 2016-01-12 公開日 2017-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid. To Be Published
5HBS	Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol at 0.89 angstrom. 分子名称: RETINOL, Retinol-binding protein 1 著者 Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. 登録日 2016-01-02 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.89 Å) 主引用文献 Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J.Biol.Chem., 291, 2016
5HA1	Crystal structure of human cellular retinol binding protein 1 in complex with retinylamine 分子名称: (2~{E},4~{E},6~{E},8~{E})-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-amine, Retinol-binding protein 1 著者 Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. 登録日 2015-12-29 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J.Biol.Chem., 291, 2016
5H9A	Crystal structure of the Apo form of human cellular retinol binding protein 1 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Retinol-binding protein 1 著者 Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. 登録日 2015-12-26 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.381 Å) 主引用文献 Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J.Biol.Chem., 291, 2016
5H8T	Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol 分子名称: RETINOL, Retinol-binding protein 1 著者 Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. 登録日 2015-12-23 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J.Biol.Chem., 291, 2016
5FFH	Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nossoni, Z, Nosrati, M, Geiger, J.H. 登録日 2015-12-18 公開日 2016-12-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal at 1.68 Angstrom Resolution To Be Published
5FEN	Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nossoni, Z, Nosrati, M, Geiger, J.H. 登録日 2015-12-17 公開日 2016-12-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution To Be Published
5FAZ	Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nosrati, M, Nossoni, Z, Geiger, J.H. 登録日 2015-12-13 公開日 2016-12-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution To Be Published
5F7G	Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nosrati, M, Nossoni, Z, Geiger, J.H. 登録日 2015-12-08 公開日 2016-12-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution To Be Published
5F6B	Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nosrati, M, Nossoni, Z, Geiger, J.H. 登録日 2015-12-05 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal at 1.31 Angstrom Resolution To Be Published
5F58	Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution 分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2 著者 Nosrati, M, Nossoni, Z, Geiger, J.H. 登録日 2015-12-04 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution To Be Published
5EDC	human FABP4 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid at 1.29A 分子名称: 6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte, ... 著者 Rudolph, M.G, Ehler, A. 登録日 2015-10-21 公開日 2016-03-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 A Real-World Perspective on Molecular Design. J.Med.Chem., 59, 2016
5EDB	human fatty acid binding protein 4 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid at 1.18A 分子名称: 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte 著者 Rudolph, M.G, Ehler, A. 登録日 2015-10-21 公開日 2016-03-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 A Real-World Perspective on Molecular Design. J.Med.Chem., 59, 2016
5DPQ	Crystal Structure of E72A mutant of domain swapped dimer Human Cellular Retinol Binding Protein 分子名称: ACETATE ION, Retinol-binding protein 2 著者 Assar, Z, Nossoni, Z, Wang, W, Geiger, J.H, Borhan, B. 登録日 2015-09-14 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.775 Å) 主引用文献 Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016
5DG4	Crystal structure of monomer human cellular retinol binding protein II-Y60L 分子名称: ACETATE ION, Retinol-binding protein 2 著者 Assar, Z, Nossoni, Z, Wang, W, Gieger, J.H, Borhan, B. 登録日 2015-08-27 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure, 24, 2016
5D8J	Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes. 分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ... 著者 Doyle, C, Birrane, G. 登録日 2015-08-17 公開日 2016-01-13 最終更新日 2017-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015
5D45	Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid 分子名称: 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte 著者 Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. 登録日 2015-08-07 公開日 2016-06-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
5D48	Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid 分子名称: 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy)phenyl]-1H-indol-1-yl}propanoic acid, Fatty acid-binding protein, adipocyte, ... 著者 Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. 登録日 2015-08-07 公開日 2016-06-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
5D4A	Crystal Structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl)propanoic acid 分子名称: 3-(2-phenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte 著者 Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. 登録日 2015-08-07 公開日 2016-06-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016

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