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PDB: 4 results
6V90
Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 12
Descriptor:
(2R)-2-{[2-(4-cyanophenyl)ethyl]amino}-N-[5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]-2-phenylacetamide, CHLORIDE ION, Histone acetyltransferase p300, ...
Authors:
Gardberg, A.S.
Deposit date:
2019-12-12
Release date:
2020-04-01
Last modified:
2024-04-03
Method:
X-RAY DIFFRACTION (2.04 Å)
Cite:
Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Chemmedchem, 15, 2020
6V8N
Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 17
Descriptor:
(2R)-2-{[(2S)-2-(4-cyanophenyl)propyl]amino}-N-[5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]-2-phenylacetamide, CHLORIDE ION, Histone acetyltransferase p300, ...
Authors:
Gardberg, A.S
,
Wilson, J.E.
Deposit date:
2019-12-11
Release date:
2020-04-01
Last modified:
2024-04-03
Method:
X-RAY DIFFRACTION (2.3 Å)
Cite:
Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Chemmedchem, 15, 2020
6V8K
Crystal structure of the p300 acetyltransferase domain with peptide-competitive inhibitor 2
Descriptor:
1-(2-methyl-1H-indol-3-yl)-2-[(2R)-2-methylpiperidin-1-yl]ethan-1-one, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:
Gardberg, A.S.
Deposit date:
2019-12-11
Release date:
2020-04-01
Last modified:
2024-04-03
Method:
X-RAY DIFFRACTION (1.84 Å)
Cite:
Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Chemmedchem, 15, 2020
6V8B
Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 1
Descriptor:
4-(2-{[(1R)-2-(1H-indol-3-yl)-2-oxo-1-phenylethyl]amino}ethyl)benzene-1-sulfonamide, CHLORIDE ION, Histone acetyltransferase p300, ...
Authors:
Gardberg, A.S.
Deposit date:
2019-12-10
Release date:
2020-04-01
Last modified:
2024-04-03
Method:
X-RAY DIFFRACTION (3.13 Å)
Cite:
Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Chemmedchem, 15, 2020
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건을2024-05-15부터공개중