2XT6
 
 | | Crystal structure of Mycobacterium smegmatis alpha-ketoglutarate decarboxylase homodimer (orthorhombic form) | | Descriptor: | 2-OXOGLUTARATE DECARBOXYLASE, CALCIUM ION, MAGNESIUM ION, ... | | Authors: | Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M. | | Deposit date: | 2010-10-05 | | Release date: | 2011-06-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism.
Chem.Biol., 18, 2011
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2F6L
 | | X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis | | Descriptor: | Chorismate mutase | | Authors: | Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E. | | Deposit date: | 2005-11-29 | | Release date: | 2005-12-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
J.Bacteriol., 188, 2006
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1K44
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1ZEL
 | | Crystal structure of RV2827C protein from Mycobacterium tuberculosis | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, FORMIC ACID, ... | | Authors: | Janowski, R, Panjikar, S, Mueller-dieckmann, J, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-04-19 | | Release date: | 2006-05-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis.
J Struct Funct Genomics, 10, 2009
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4JXB
 | | RipD (Rv1566c) from Mycobacterium tuberculosis: a non-catalytic NlpC/p60 domain protein, adaptation to peptidoglycan-binding function | | Descriptor: | ACETATE ION, Invasion-associated protein | | Authors: | Both, D, Steiner, E.M, Schnell, R, Schneider, G. | | Deposit date: | 2013-03-28 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function.
Biochem.J., 457, 2014
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3EUL
 | | Structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis | | Descriptor: | CHLORIDE ION, POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-binding response regulator, LuxR family) | | Authors: | Schneider, G, Schnell, R, Agren, D. | | Deposit date: | 2008-10-10 | | Release date: | 2008-11-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | 1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 64, 2008
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7YY0
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7YY5
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4JD6
 | | Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin | | Descriptor: | COENZYME A, Enhanced intracellular survival protein, TOBRAMYCIN | | Authors: | Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V. | | Deposit date: | 2013-02-23 | | Release date: | 2013-10-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase eis.
Chembiochem, 14, 2013
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1X74
 | | Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis- mutational and structural characterization of the fold and active site | | Descriptor: | 2-methylacyl-CoA racemase, GLYCEROL, PHOSPHATE ION | | Authors: | Kalle, S, Bhaumik, P, Schmitz, W, Kotti, T.J, Conzelmann, E, Wierenga, R.K, Hiltunen, J.K. | | Deposit date: | 2004-08-13 | | Release date: | 2005-01-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | {alpha}-Methylacyl-CoA Racemase from Mycobacterium tuberculosis: MUTATIONAL AND STRUCTURAL CHARACTERIZATION OF THE ACTIVE SITE AND THE FOLD
J.Biol.Chem., 280, 2005
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3X3N
 | | Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P21 | | Descriptor: | CALCIUM ION, ESX-1 secretion system protein EccB1 | | Authors: | Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. | | Deposit date: | 2015-01-24 | | Release date: | 2015-12-09 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase.
Faseb J., 29, 2015
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3LO7
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2QBV
 | | Crystal Structure of Intracellular Chorismate Mutase from Mycobacterium Tuberculosis | | Descriptor: | CHORISMATE MUTASE | | Authors: | Ladner, J.E, Reddy, P.T, Kim, S.K, Reddy, S.-K, Nelson, B.C. | | Deposit date: | 2007-06-18 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis.
Febs J., 275, 2008
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3E4W
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2H5X
 | | RuvA from Mycobacterium tuberculosis | | Descriptor: | GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA | | Authors: | Prabu, J.R, Thamotharan, S, Khanduja, J.S, Alipio, E.Z, Kim, C.Y, Waldo, G.S, Terwilliger, T.C, Segelke, B, Lekin, T, Toppani, D, Hung, L.W, Yu, M, Bursey, E, Muniyappa, K, Chandra, N.R, Vijayan, M. | | Deposit date: | 2006-05-28 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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2GWR
 | | Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis | | Descriptor: | CALCIUM ION, DNA-binding response regulator mtrA, GLYCEROL | | Authors: | Friedland, N, Mack, T.R, Yu, M, Bursey, E.H, Hung, L.W, Stock, A.M, Waldo, G.S, Terwilliger, T.C. | | Deposit date: | 2006-05-05 | | Release date: | 2006-05-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation.
Biochemistry, 46, 2007
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2G9W
 | | Crystal Structure of Rv1846c, a Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis | | Descriptor: | CHLORIDE ION, conserved hypothetical protein | | Authors: | Saul, F.A, Haouz, A, Fiez-Vandal, C, Shepard, W, Alzari, P.M. | | Deposit date: | 2006-03-07 | | Release date: | 2007-03-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis
Mol.Microbiol., 71, 2009
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4AUT
 | | Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis | | Descriptor: | DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C. | | Deposit date: | 2012-05-21 | | Release date: | 2012-09-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis.
Sci. Transl. Med., 4, 2012
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8WFX
 | | Cryo-EM structure of CRISPR-Csm effector complex from Mycobacterium canettii | | Descriptor: | CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ... | | Authors: | Huo, Y, Ma, X, Jiang, T. | | Deposit date: | 2023-09-20 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Type-III-A structure of mycobacteria CRISPR-Csm complexes involving atypical crRNAs.
Int.J.Biol.Macromol., 260, 2024
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6QR4
 | | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor | | Descriptor: | 5-azanyl-3-[1-[[(2~{R})-1-methylpiperidin-2-yl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile, tRNA (guanine-N(1)-)-methyltransferase | | Authors: | Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L. | | Deposit date: | 2019-02-19 | | Release date: | 2019-09-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.
J.Med.Chem., 62, 2019
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5E38
 | | Structural basis of mapping the spontaneous mutations with 5-flourouracil in uracil phosphoribosyltransferase from Mycobacterium tuberculosis | | Descriptor: | Uracil phosphoribosyltransferase | | Authors: | Ghode, P, Jobichen, C, Ramachandran, S, Bifani, P, Sivaraman, J. | | Deposit date: | 2015-10-02 | | Release date: | 2015-10-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of mapping the spontaneous mutations with 5-flurouracil in uracil phosphoribosyltransferase from Mycobacterium tuberculosis
Biochem.Biophys.Res.Commun., 467, 2015
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4OKC
 | | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis | | Descriptor: | LysM domain protein | | Authors: | Patra, D, Mishra, P, Surolia, A, Vijayan, M. | | Deposit date: | 2014-01-22 | | Release date: | 2014-07-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis.
Glycobiology, 24, 2014
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1YLK
 | | Crystal Structure of Rv1284 from Mycobacterium tuberculosis in Complex with Thiocyanate | | Descriptor: | Hypothetical protein Rv1284/MT1322, THIOCYANATE ION, ZINC ION | | Authors: | Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE) | | Deposit date: | 2005-01-19 | | Release date: | 2005-03-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.
J.Biol.Chem., 280, 2005
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4MFI
 | | Crystal structure of Mycobacterium tuberculosis UgpB | | Descriptor: | Sn-glycerol-3-phosphate ABC transporter substrate-binding protein UspB | | Authors: | Jiang, D, Bartlam, M, Rao, Z. | | Deposit date: | 2013-08-28 | | Release date: | 2014-07-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural analysis of Mycobacterium tuberculosis ATP-binding cassette transporter subunit UgpB reveals specificity for glycerophosphocholine
Febs J., 281, 2014
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7CL4
 | | The crystal structure of KanJ in complex with N-oxalylglycine | | Descriptor: | Kanamycin B dioxygenase, N-OXALYLGLYCINE, NICKEL (II) ION | | Authors: | Kitayama, Y, Miyanaga, A, Kudo, F, Eguchi, T. | | Deposit date: | 2020-07-20 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis.
Chembiochem, 22, 2021
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