PDB: 1732 resultsInfo pagesStatus searchChemie searchBIRD

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2B7D	Factor VIIa Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, and Efficacy in a Baboon Thrombosis Model Descriptor: (2R)-2-[5-(5-CARBAMIMIDOYL-1H-BENZOIMIDAZOL-2-YL)-6,2'-DIHYDROXY-5'-UREIDOMETHYL-BIPHENYL-3-YL]-SUCCINIC ACID, Coagulation factor VII, Tissue factor Authors: Young, W.B, Mordenti, J, Torkelson, S, Shrader, W.D, Kolesnikov, A, Rai, R, Liu, L, Hu, H, Leahy, E.M, Green, M.J, Sprengeler, P.A, Katz, B.A, Yu, C, Janc, J.W, Elrod, K.C, Marzec, U.M, Hanson, S.R. Deposit date: 2005-10-04 Release date: 2006-02-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model. Bioorg.Med.Chem.Lett., 16, 2006
1PMK	KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES Descriptor: PLASMINOGEN KRINGLE 4 Authors: Padmanabhan, K, Tulinsky, A. Deposit date: 1994-04-25 Release date: 1994-06-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Kringle-kringle interactions in multimer kringle structures. Protein Sci., 3, 1994
1PG7	Murine 6A6 Fab in complex with humanized anti-Tissue Factor D3H44 Fab Descriptor: humanized antibody D3H44, murine antibody 6A6 Fab fragment Authors: Eigenbrot, C, Meng, Y.G, Krishnamurthy, R, Lipari, M.T, Presta, L, Devaux, B, Wong, T, Moran, P, Bullens, S, Kirchhofer, D. Deposit date: 2003-05-27 Release date: 2003-08-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation. J.Mol.Biol., 331, 2003
1PFX	PORCINE FACTOR IXA Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, FACTOR IXA Authors: Brandstetter, H, Bauer, M, Huber, R, Lollar, P, Bode, W. Deposit date: 1995-07-19 Release date: 1996-08-17 Last modified: 2013-02-27 Method: X-RAY DIFFRACTION (3 Å) Cite: X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. Proc.Natl.Acad.Sci.USA, 92, 1995
1PML	KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES Descriptor: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR KRINGLE 2 Authors: Padmanabhan, K, Tulinsky, A. Deposit date: 1994-04-25 Release date: 1994-06-22 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Kringle-kringle interactions in multimer kringle structures. Protein Sci., 3, 1994
1PK2	SOLUTION STRUCTURE OF THE TISSUE-TYPE PLASMINOGEN ACTIVATOR KRINGLE 2 DOMAIN COMPLEXED TO 6-AMINOHEXANOIC ACID AN ANTIFIBRINOLYTIC DRUG Descriptor: 6-AMINOHEXANOIC ACID, TISSUE-TYPE PLASMINOGEN ACTIVATOR Authors: Llinas, M, Byeon, I.-J.L. Deposit date: 1991-09-16 Release date: 1994-01-31 Last modified: 2024-10-23 Method: SOLUTION NMR Cite: Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug. J.Mol.Biol., 222, 1991
1TPK	CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION Descriptor: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR Authors: De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A. Deposit date: 1991-09-24 Release date: 1992-07-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. Biochemistry, 31, 1992

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