6NN1
 
 | | Xanthomonas citri PGM Apo-Dephospho | | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Stiers, K.M, Beamer, L.J. | | Deposit date: | 2019-01-14 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and dynamical description of the enzymatic reaction of a phosphohexomutase.
Struct Dyn., 6, 2019
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7P04
 | | Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation with ADP/ATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Pleiotropic ABC efflux transporter of multiple drugs | | Authors: | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | | Deposit date: | 2021-06-29 | | Release date: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5.
Nat Commun, 12, 2021
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6WI6
 | | Crystal structure of plantacyclin B21AG | | Descriptor: | MALONATE ION, Plantacyclin B21AG | | Authors: | Smith, A.T, Gor, M.C, Vezina, B, McMahon, R, King, G, Panjikar, S, Rehm, B, Martin, J. | | Deposit date: | 2020-04-08 | | Release date: | 2021-01-06 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity.
Sci Rep, 10, 2020
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8E7F
 | | Crystal structure of the autotransporter Ssp from Serratia marcescens. | | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Extracellular serine protease, ... | | Authors: | Hor, L, Pilapitiya, A, Panjikar, S, Paxman, J.J, Heras, B. | | Deposit date: | 2022-08-23 | | Release date: | 2023-03-08 | | Last modified: | 2023-03-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
Nat Commun, 14, 2023
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6Z9E
 | | 1.55 A structure of human apoferritin obtained from data subset of Titan Mono-BCOR microscope | | Descriptor: | Ferritin heavy chain, SODIUM ION | | Authors: | Yip, K.M, Fischer, N, Paknia, E, Chari, A, Stark, H. | | Deposit date: | 2020-06-03 | | Release date: | 2020-06-24 | | Last modified: | 2021-02-10 | | Method: | ELECTRON MICROSCOPY (1.55 Å) | | Cite: | Atomic-resolution protein structure determination by cryo-EM.
Nature, 587, 2020
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6NQF
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8E5N
 | | Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 10 | | Descriptor: | 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION | | Authors: | Palte, R.L, Gathiaka, S. | | Deposit date: | 2022-08-22 | | Release date: | 2023-03-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.538 Å) | | Cite: | Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
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5K7H
 | | Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A | | Descriptor: | CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ... | | Authors: | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | | Deposit date: | 2016-05-26 | | Release date: | 2016-12-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
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8E5M
 | | Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6 | | Descriptor: | 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION | | Authors: | Palte, R.L, Gathiaka, S. | | Deposit date: | 2022-08-22 | | Release date: | 2023-03-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
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6NIL
 | | cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex | | Descriptor: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3F, Virion infectivity factor, ... | | Authors: | Hu, Y, Xiong, Y. | | Deposit date: | 2018-12-29 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.
Nat.Struct.Mol.Biol., 26, 2019
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6Z44
 | | Crystal structure of the cAMP-dependent protein kinase A in complex with phenol | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, DIMETHYL SULFOXIDE, PHENOL, ... | | Authors: | Oebbeke, M, Heine, A, Klebe, G. | | Deposit date: | 2020-05-22 | | Release date: | 2020-12-09 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Fragment Binding to Kinase Hinge: If Charge Distribution and Local pK a Shifts Mislead Popular Bioisosterism Concepts.
Angew.Chem.Int.Ed.Engl., 60, 2021
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6WXG
 | | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Reversed conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | | Authors: | Herrmann, T, Harrison, S.C, Jenni, S. | | Deposit date: | 2020-05-10 | | Release date: | 2021-01-20 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Functional refolding of the penetration protein on a non-enveloped virus.
Nature, 590, 2021
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6NN3
 | | Structure of parvovirus B19 decorated with Fab molecules from a human antibody | | Descriptor: | Fab monoclonal antibody 860-55D, heavy chain, light chain, ... | | Authors: | Rossmann, M.G, Sun, Y, Klose, T, Liu, Y. | | Deposit date: | 2019-01-14 | | Release date: | 2019-02-13 | | Last modified: | 2020-03-04 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
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8DMY
 | | Cryo-EM structure of cardiac muscle alpha-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | | Deposit date: | 2022-07-09 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Structural insights into actin isoforms.
Elife, 12, 2023
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6NQE
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7QAB
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8DMX
 | | Cryo-EM structure of skeletal muscle alpha-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | | Deposit date: | 2022-07-08 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Structural insights into actin isoforms.
Elife, 12, 2023
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8DNH
 | | Cryo-EM structure of nonmuscle beta-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Structural insights into actin isoforms.
Elife, 12, 2023
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5JXZ
 | | A low magnesium structure of the isochorismate synthase, EntC | | Descriptor: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, Isochorismate synthase EntC, ... | | Authors: | Meneely, K.M, Sundlov, J.A, Gulick, A.M, Lamb, A.L. | | Deposit date: | 2016-05-13 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
J.Am.Chem.Soc., 138, 2016
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5JZD
 | | A re-refinement of the isochorismate synthase EntC | | Descriptor: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, Isochorismate synthase EntC, MAGNESIUM ION | | Authors: | Meneely, K.M, Lamb, A.L. | | Deposit date: | 2016-05-16 | | Release date: | 2016-07-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
J.Am.Chem.Soc., 138, 2016
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6ZIX
 | | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter P1flhDC in the presence of phosphomimetic BeF3- | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P1flhDC promoter sequence of 23 bp, ... | | Authors: | Huesa, J, Marina, A, Casino, P. | | Deposit date: | 2020-06-26 | | Release date: | 2021-02-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
Nucleic Acids Res., 49, 2021
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6ZIL
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6ZJ2
 | | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter rprA in the presence of phosphomimetic BeF3- | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*TP*CP*AP*GP*AP*TP*TP*CP*GP*TP*CP*TP*CP*AP*AP*TP*AP*GP*G)-3'), MAGNESIUM ION, ... | | Authors: | Huesa, J, Marina, A, Casino, P. | | Deposit date: | 2020-06-27 | | Release date: | 2021-02-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
Nucleic Acids Res., 49, 2021
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6NOQ
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6NP8
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