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4IEX	unliganded room-temp Cysteine Dioxygenase at pH 6.2 Descriptor: Cysteine dioxygenase type 1, FE (II) ION Authors: Driggers, C.M, Cooley, R.B, Karplus, P.A. Deposit date: 2012-12-13 Release date: 2013-06-26 Last modified: 2013-09-11 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH. J.Mol.Biol., 425, 2013
4ODS	Unliganded Fab structure of lipid A-specific antibody S55-3 Descriptor: S55-3 Fab (IgG2b) heavy chain Authors: Haji-Ghassemi, O, Evans, S.V. Deposit date: 2014-01-10 Release date: 2015-07-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J.Biol.Chem., 290, 2015
1PEB	LIGAND-FREE HIGH-AFFINITY MALTOSE-BINDING PROTEIN Descriptor: Maltose-binding periplasmic protein Authors: Telmer, P.G, Shilton, B.H. Deposit date: 2003-05-21 Release date: 2003-08-12 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Insights into the Conformational Equilibria of Maltose-binding Protein by Analysis of High Affinity Mutants. J.Biol.Chem., 278, 2003
5AIC	ligand complex structure of soluble epoxide hydrolase Descriptor: 7-methyl-2H-1,4-benzothiazin-3(4H)-one, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-02-12 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AK4	ligand complex structure of soluble epoxide hydrolase Descriptor: 3-METHYL-4-PHENYL-1H-PYRAZOLE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-02 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AI4	ligand complex structure of soluble epoxide hydrolase Descriptor: 2-[(5-BROMO-2-PYRIDYL)-METHYL-AMINO]ETHANOL, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-02-12 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AKG	ligand complex structure of soluble epoxide hydrolase Descriptor: 5-(2-thienyl)-1,3,4-thiadiazol-2-amine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-03 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AKX	ligand complex structure of soluble epoxide hydrolase Descriptor: 5-iodanyl-1H-indazole, DIMETHYL SULFOXIDE, SOLUBLE EPOXIDE HYDROLASE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-05 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AI0	Ligand complex structure of soluble epoxide hydrolase Descriptor: 4-PHENYL-1,2,5-OXADIAZOL-3-AMINE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-02-11 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALL	ligand complex structure of soluble epoxide hydrolase Descriptor: DIMETHYL SULFOXIDE, SOLUBLE EPOXIDE HYDROLASE, SULFATE ION, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALS	ligand complex structure of soluble epoxide hydrolase Descriptor: BIFUNCTIONAL EPOXIDE HYDROLASE 2, N-CYCLOPENTYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-3H-IMIDAZO[4,5-B]PYRIDINE-7-SULFONAMIDE, SULFATE ION Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALV	ligand complex structure of soluble epoxide hydrolase Descriptor: 3-(3-fluorophenyl)-1H-pyrazole, BIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALZ	ligand complex structure of soluble epoxide hydrolase Descriptor: 1-(1-adamantyl)-3-(1-methylsulfonylpiperidin-4-yl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALX	ligand complex structure of soluble epoxide hydrolase Descriptor: 5-(3-ethylsulfanylphenyl)thiophene-2-carboxamide, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALQ	ligand complex structure of soluble epoxide hydrolase Descriptor: 1-(3-PHENYL-1H-PYRAZOL-5-YL)CYCLOPENTANOL, BIFUNCTIONAL EPOXIDE HYDROLASE 2, SULFATE ION Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AM2	ligand complex structure of soluble epoxide hydrolase Descriptor: 7-METHYL-2H-ISOQUINOLIN-1-ONE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-08 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AI8	ligand complex structure of soluble epoxide hydrolase Descriptor: 6-methyl-1,3-benzothiazol-2-amine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-02-12 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AK3	ligand complex structure of soluble epoxide hydrolase Descriptor: BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, INDAN-2-AMINE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-02 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AKI	ligand complex structure of soluble epoxide hydrolase Descriptor: BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Oster, L, Tapani, S, Xue, Y, Kack, H. Deposit date: 2015-03-03 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5NI7	Ligand complex of RORg LBD Descriptor: DIMETHYL SULFOXIDE, Nuclear receptor ROR-gamma, SODIUM ION, ... Authors: Xue, Y, Aagaard, A, Narjes, F. Deposit date: 2017-03-23 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018
5NIB	Ligand complex of RORg LBD Descriptor: DIMETHYL SULFOXIDE, Nuclear receptor ROR-gamma, SODIUM ION, ... Authors: Xue, Y, Aagaard, A, Narjes, F. Deposit date: 2017-03-23 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018
5NI5	Ligand complex of RORg LBD Descriptor: Nuclear receptor ROR-gamma, SODIUM ION, tethered SRC2-2 peptide, ... Authors: Xue, Y, Aagaard, A, Narjes, F. Deposit date: 2017-03-23 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018
5NI8	Ligand complex of RORg LBD Descriptor: 2-(4-ethylsulfonylphenyl)-~{N}-[4-(2-phenylmethoxypyridin-3-yl)thiophen-2-yl]ethanamide, Nuclear receptor ROR-gamma, SODIUM ION, ... Authors: Xue, Y, Aagaard, A, Narjes, F. Deposit date: 2017-03-23 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018
6DGV	iGABASnFR Fluorescent GABA Sensor precursor Descriptor: Fluorescent GABA Sensor precursor Authors: Marvin, J.S, Looger, L.L. Deposit date: 2018-05-18 Release date: 2019-04-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A genetically encoded fluorescent sensor for in vivo imaging of GABA. Nat.Methods, 16, 2019
4LBD	LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961 Descriptor: 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, RETINOIC ACID RECEPTOR GAMMA Authors: Klaholz, B.P, Renaud, J.-P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) Deposit date: 1998-02-04 Release date: 1999-03-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Conformational adaptation of agonists to the human nuclear receptor RAR gamma. Nat.Struct.Biol., 5, 1998

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