8XQU
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![BU of 8xqu by Molmil](/molmil-images/mine/8xqu) | The Crystal Structure of ClpC1-NTD from Biortus. | Descriptor: | 1,2-ETHANEDIOL, ATP-dependent Clp protease ATP-binding subunit ClpC1, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Ni, C. | Deposit date: | 2024-01-05 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Crystal Structure of ClpC1-NTD from Biortus. To Be Published
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6H6T
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4C8M
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![BU of 4c8m by Molmil](/molmil-images/mine/4c8m) | Binary complex of the large fragment of DNA polymerase I from Thermus Aquaticus with the aritificial base pair d5SICS-dNaM at the postinsertion site (sequence context 2) | Descriptor: | GLYCEROL, LARGE FRAGMENT OF TAQ DNA POLYMERASE I, MAGNESIUM ION, ... | Authors: | Betz, K, Malyshev, D.A, Lavergne, T, Welte, W, Diederichs, K, Romesberg, F.E, Marx, A. | Deposit date: | 2013-10-01 | Release date: | 2013-12-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.568 Å) | Cite: | Structural Insights Into DNA Replication without Hydrogen Bonds. J.Am.Chem.Soc., 135, 2013
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5ZVB
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![BU of 5zvb by Molmil](/molmil-images/mine/5zvb) | APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dT9) | Descriptor: | APEBEC3F/ssDNA-T9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*T)-3'), ... | Authors: | Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y. | Deposit date: | 2018-05-09 | Release date: | 2018-11-21 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA Chin.J.Chem., 36, 2018
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6U3P
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![BU of 6u3p by Molmil](/molmil-images/mine/6u3p) | Binary complex of native hAChE with oxime reactivator LG-703 | Descriptor: | (2E,2'E)-N,N'-[1,4-diazepane-1,4-diyldi(ethane-2,1-diyl)]bis[2-(hydroxyimino)acetamide], Acetylcholinesterase, DIMETHYL SULFOXIDE | Authors: | Kovalevsky, A, Gerlits, O, Radic, Z. | Deposit date: | 2019-08-22 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase. J.Biol.Chem., 295, 2020
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5XFR
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![BU of 5xfr by Molmil](/molmil-images/mine/5xfr) | Ternary complex of MTF2, DNA and histone | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... | Authors: | Wang, Z, Li, H. | Deposit date: | 2017-04-11 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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5ZVA
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![BU of 5zva by Molmil](/molmil-images/mine/5zva) | APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9) | Descriptor: | APEBEC3F/ssDNA-C9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3'), ... | Authors: | Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y. | Deposit date: | 2018-05-09 | Release date: | 2018-11-21 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA Chin.J.Chem., 36, 2018
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5ZVT
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![BU of 5zvt by Molmil](/molmil-images/mine/5zvt) | Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly | Descriptor: | C-terminus of outer capsid protein VP5, Core protein VP6, MYRISTIC ACID, ... | Authors: | Liu, H, Fang, Q, Cheng, L. | Deposit date: | 2018-05-12 | Release date: | 2018-07-04 | Last modified: | 2018-07-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XFP
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![BU of 5xfp by Molmil](/molmil-images/mine/5xfp) | Binary complex of PHF1 and a double stranded DNA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, ... | Authors: | Wang, Z, Li, H. | Deposit date: | 2017-04-11 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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5XFQ
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![BU of 5xfq by Molmil](/molmil-images/mine/5xfq) | Ternary complex of PHF1, a DNA duplex and a histone peptide | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ... | Authors: | Wang, Z, Li, H. | Deposit date: | 2017-04-11 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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7WKH
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![BU of 7wkh by Molmil](/molmil-images/mine/7wkh) | the grass carp IFNa | Descriptor: | Interferon | Authors: | Zou, J, WANG, J, Wang, Z. | Deposit date: | 2022-01-09 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish. Front Immunol, 13, 2022
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7QWQ
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![BU of 7qwq by Molmil](/molmil-images/mine/7qwq) | Ternary complex of ribosome nascent chain with SRP and NAC | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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5Y91
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![BU of 5y91 by Molmil](/molmil-images/mine/5y91) | |
5Y7T
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![BU of 5y7t by Molmil](/molmil-images/mine/5y7t) | Quaternary complex of AsqJ-Fe3+-2OG-D-cyclopeptin | Descriptor: | (3R)-4-methyl-3-(phenylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione, 2-OXOGLUTARIC ACID, FE (III) ION, ... | Authors: | Liao, H.J. | Deposit date: | 2017-08-18 | Release date: | 2018-01-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation. Angew. Chem. Int. Ed. Engl., 57, 2018
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7WQY
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7KCI
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![BU of 7kci by Molmil](/molmil-images/mine/7kci) | DETERMINANTS OF REPRESSOR/OPERATOR RECOGNITION FROM THE STRUCTURE OF THE TRP OPERATOR BINDING SITE | Descriptor: | Self-complementary deoxyoligonucleotide decamer d(CCACTAGTGG) | Authors: | Shakked, Z, Guzikevich-Guerstein, G, Frolow, F, Rabinovich, D, Joachimiak, A, Sigler, P.B. | Deposit date: | 1994-09-12 | Release date: | 2020-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Determinants of repressor/operator recognition from the structure of the trp operator binding site. Nature, 368, 1994
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5Y7R
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![BU of 5y7r by Molmil](/molmil-images/mine/5y7r) | Quaternary complex of AsqJ-Fe3+-2OG-cyclopeptin | Descriptor: | 2-OXOGLUTARIC ACID, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | Authors: | Liao, H.J, Lin, T.S. | Deposit date: | 2017-08-17 | Release date: | 2018-01-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation. Angew. Chem. Int. Ed. Engl., 57, 2018
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5ZLZ
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![BU of 5zlz by Molmil](/molmil-images/mine/5zlz) | Structure of tPA and PAI-1 | Descriptor: | GLYCEROL, Plasminogen activator inhibitor 1, Tissue-type plasminogen activator | Authors: | Min, L, Huang, M. | Deposit date: | 2018-03-31 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.581 Å) | Cite: | Development of a PAI-1 trapping agent (PAItrap2) based on inactivated tPA-SPD and the crystal structure of PAItrap2 in complex with PAI-1 To Be Published
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8SF2
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![BU of 8sf2 by Molmil](/molmil-images/mine/8sf2) | Crystal structure of the engineered SsoPox variant IG7 | Descriptor: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | Authors: | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | Deposit date: | 2023-04-10 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase To Be Published
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8SFA
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![BU of 8sfa by Molmil](/molmil-images/mine/8sfa) | Crystal structure of the engineered SsoPox variant IIIC1 | Descriptor: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION | Authors: | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | Deposit date: | 2023-04-10 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase To Be Published
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5WTZ
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![BU of 5wtz by Molmil](/molmil-images/mine/5wtz) | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NAD+ | Descriptor: | Binary enterotoxin of Clostridium perfringens component a, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | Deposit date: | 2016-12-15 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
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5BYI
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6CZW
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![BU of 6czw by Molmil](/molmil-images/mine/6czw) | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, {2-bromo-3-(3-chloro-5-fluorophenoxy)-6-[(difluoromethyl)sulfonyl]phenyl}methanol | Authors: | Du, X. | Deposit date: | 2018-04-09 | Release date: | 2018-10-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex To Be Published
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5ZVS
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6D0B
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![BU of 6d0b by Molmil](/molmil-images/mine/6d0b) | Crystal structure of PT1614 bound to HIF2a-B*:ARNT-B* complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-2-nitro-4-[(trifluoromethyl)sulfonyl]aniline | Authors: | Du, X. | Deposit date: | 2018-04-10 | Release date: | 2018-10-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of PT1614 bound to HIF2a-B*:ARNT-B* complex To Be Published
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