PDB: 4050 resultsInfo pagesStatus searchChemie searchBIRD

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6ACG	Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 1 Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Gui, M, Song, W. Deposit date: 2018-07-26 Release date: 2018-08-08 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (5.4 Å) Cite: Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog., 14, 2018
6ACJ	Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 2 Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Gui, M, Song, W. Deposit date: 2018-07-26 Release date: 2018-08-08 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog., 14, 2018
6ACK	Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 3 Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Gui, M, Song, W. Deposit date: 2018-07-26 Release date: 2018-08-08 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog., 14, 2018
6SWV	Trypsin fast data collection Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... Authors: von Stetten, D, Mueller-Dieckmann, C. Deposit date: 2019-09-24 Release date: 2020-05-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.432 Å) Cite: ID30A-3 (MASSIF-3) - a beamline for macromolecular crystallography at the ESRF with a small intense beam. J.Synchrotron Radiat., 27, 2020
1Y3W	TRYPSIN INHIBITOR COMPLEX Descriptor: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL-1-ETHYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE, CALCIUM ION, Trypsinogen, ... Authors: Fokkens, J, Klebe, G. Deposit date: 2004-11-26 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates. Angew.Chem.Int.Ed.Engl., 45, 2006
1Y3X	TRYPSIN INHIBITOR COMPLEX Descriptor: (1R,3AS,4R,8AS,8BR)-4-{5-(PHENYL[1,3]DIOXOL-5-YLMETHYL)-4-ETHYL-2,3,3-TRIMETHYL-6-OXO-OCTAHYDRO-PYRROLO[3,4-C]PYRROL-1-YL}-BENZAMIDINE, CALCIUM ION, Trypsinogen, ... Authors: Fokkens, J, Klebe, G. Deposit date: 2004-11-26 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates. Angew.Chem.Int.Ed.Engl., 45, 2006
1Y3Y	TRYPSIN INHIBITOR COMPLEX Descriptor: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YL-1-CYCLOPROPYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE, CALCIUM ION, Trypsin, ... Authors: Fokkens, J, Klebe, G. Deposit date: 2004-11-26 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates. Angew.Chem.Int.Ed.Engl., 45, 2006
1Y3V	Trypsin Inhibitor Complex Descriptor: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YL-1-CYCLOPROPYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE, CALCIUM ION, Trypsin, ... Authors: Fokkens, J, Klebe, G. Deposit date: 2004-11-26 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates. Angew.Chem.Int.Ed.Engl., 45, 2006
2HDN	Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution Descriptor: Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. Deposit date: 2006-06-20 Release date: 2006-10-31 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu. Acta Crystallogr.,Sect.D, 62, 2006
6ACC	Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with three RBD in down conformation Descriptor: Spike glycoprotein Authors: Gui, M, Song, W. Deposit date: 2018-07-26 Release date: 2018-08-08 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog., 14, 2018
6ACD	Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with one RBD in up conformation Descriptor: Spike glycoprotein Authors: Gui, M, Song, W. Deposit date: 2018-07-26 Release date: 2018-08-08 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog., 14, 2018
2D26	Active site distortion is sufficient for proteinase inhibit second crystal structure of covalent serpin-proteinase complex Descriptor: Alpha-1-antitrypsin, Elastase-1 Authors: Dementiev, A, Dobo, J, Gettins, P.G. Deposit date: 2005-09-03 Release date: 2005-11-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Active Site Distortion Is Sufficient for Proteinase Inhibition by Serpins: Structure of the covalent complex of alpha 1-proteinase inhibitor with porcine pancreatic elastase J.Biol.Chem., 281, 2006
2HCJ	Trypsin-modified Elongation Factor Tu in complex with tetracycline Descriptor: GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. Deposit date: 2006-06-16 Release date: 2006-10-31 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu. Acta Crystallogr.,Sect.D, 62, 2006
1YP9	Trypsin Inhibitor Complex Descriptor: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL)-1-BENZYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROZILIN-4-YL-BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... Authors: Fokkens, J, Obst-Sander, U, Heine, A, Diederich, F, Klebe, G. Deposit date: 2005-01-31 Release date: 2006-01-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates Angew.Chem.Int.Ed.Engl., 45, 2006
1OYQ	TRYPSIN INHIBITOR COMPLEX Descriptor: CALCIUM ION, SULFATE ION, Trypsin, ... Authors: Nar, H. Deposit date: 2003-04-07 Release date: 2003-04-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors Structure, 9, 2001
1EB2	Trypsin inhibitor complex (BPO) Descriptor: 3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPERIDINYL)-2-OXO-1-PHENYLETHYL]BENZAMIDE, CALCIUM ION, SULFATE ION, ... Authors: Wilkinson, K.W, Young, S.C, Liebeschuetz, J.W, Brady, R.L. Deposit date: 2001-07-18 Release date: 2002-02-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors J.Med.Chem., 45, 2002
3IIR	Crystal Structure of Miraculin like protein from seeds of Murraya koenigii Descriptor: Trypsin inhibitor Authors: Gahloth, D, Selvakumar, P, Shee, C, Kumar, P, Sharma, A.K. Deposit date: 2009-08-03 Release date: 2009-12-08 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Cloning, sequence analysis and crystal structure determination of a miraculin-like protein from Murraya koenigii Arch.Biochem.Biophys., 494, 2010
1G36	TRYPSIN INHIBITOR COMPLEX Descriptor: 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE, CALCIUM ION, SULFATE ION, ... Authors: Nar, H. Deposit date: 2000-10-23 Release date: 2001-10-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors. Structure, 9, 2001
2LJS	Solution structure of MCoTI-V Descriptor: Trypsin inhibitor 3 Authors: Daly, N.L, Craik, D.J. Deposit date: 2011-09-23 Release date: 2012-08-08 Last modified: 2019-12-25 Method: SOLUTION NMR Cite: Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase-Mediated Biosynthesis. Plant Cell, 24, 2012
2JZM	Chymotrypsin inhibitor C1 from Nicotiana alata Descriptor: Proteinase inhibitor Authors: Schirra, H.J, Anderson, M.A, Craik, D.J. Deposit date: 2008-01-09 Release date: 2008-11-25 Last modified: 2019-10-09 Method: SOLUTION NMR Cite: Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata. Protein Pept.Lett., 15, 2008
1QH2	CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA Descriptor: PROTEIN (TRYPSIN INHIBITOR C2) Authors: Lee, M.C.S, Scanlon, M.J, Anderson, M.A, Craik, D.J. Deposit date: 1999-05-11 Release date: 1999-05-24 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein. Nat.Struct.Biol., 6, 1999
1OO8	CRYSTAL STRUCTURE OF A1PI-PITTSBURGH IN THE NATIVE CONFORMATION Descriptor: Alpha-1-antitrypsin precursor Authors: Dementiev, A, Simonovic, M, Volz, K, Gettins, P.G. Deposit date: 2003-03-03 Release date: 2003-08-05 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases J.Biol.Chem., 278, 2003
1SHP	THE NMR SOLUTION STRUCTURE OF A KUNITZ-TYPE PROTEINASE INHIBITOR FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS Descriptor: TRYPSIN INHIBITOR Authors: Antuch, W, Berndt, K, Chavez, M, Delfin, J, Wuthrich, K. Deposit date: 1992-11-17 Release date: 1994-01-31 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: The NMR solution structure of a Kunitz-type proteinase inhibitor from the sea anemone Stichodactyla helianthus. Eur.J.Biochem., 212, 1993
1YPC	DIRECT OBSERVATION OF BETTER HYDRATION AT THE N-TERMINUS OF AN ALPHA-HELIX WITH GLYCINE RATHER THAN ALANINE AS N-CAP Descriptor: CHYMOTRYPSIN INHIBITOR 2 Authors: Harpaz, Y, Elmasry, N, Fersht, A.R, Henrick, K. Deposit date: 1993-01-10 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. Proc.Natl.Acad.Sci.USA, 91, 1994
1YPB	DIRECT OBSERVATION OF BETTER HYDRATION AT THE N-TERMINUS OF AN ALPHA-HELIX WITH GLYCINE RATHER THAN ALANINE AS N-CAP Descriptor: CHYMOTRYPSIN INHIBITOR 2 Authors: Harpaz, Y, Elmasry, N, Fersht, A.R, Henrick, K. Deposit date: 1993-01-10 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. Proc.Natl.Acad.Sci.USA, 91, 1994

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