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7T8I
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BU of 7t8i by Molmil
Crystal structure of the ImmR transcriptional regulator DNA-binding domain of Bacillus subtilis
Descriptor: Phage element (ICEBs1)transcriptional regulator (Xre family)
Authors:Caliandro, R, de Diego, I, Gomis-Ruth, F.X.
Deposit date:2021-12-16
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure report of the ImmR transcriptional regulator DNA-binding domain of the Bacillus subtilis ICEBs1 transposon.
Sci Rep, 12, 2022
6GTO
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BU of 6gto by Molmil
Structure of the AtaR antitoxin
Descriptor: DUF1778 domain-containing protein, SODIUM ION
Authors:Garcia-Pino, A, Jurenas, D.
Deposit date:2018-06-18
Release date:2019-03-06
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
6GTS
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BU of 6gts by Molmil
Structure of the AtaT-AtaR complex bound DNA
Descriptor: Acetyltransferase, DNA, DUF1778 domain-containing protein
Authors:Garcia-Pino, A, Jurenas, D.
Deposit date:2018-06-19
Release date:2019-03-06
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.357 Å)
Cite:Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
6GTR
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BU of 6gtr by Molmil
Structure of the AtaT Y144F mutant toxin bound to the C-terminus of the antitoxin AtaR and Acetyl-CoA
Descriptor: ACETYL COENZYME *A, DUF1778 domain-containing protein, GLYCEROL, ...
Authors:Garcia-Pino, A, Jurenas, D.
Deposit date:2018-06-18
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
6GTP
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BU of 6gtp by Molmil
Structure of the AtaT Y144F mutant toxin
Descriptor: ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Garcia-Pino, A, Jurenas, D.
Deposit date:2018-06-18
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
6GTQ
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BU of 6gtq by Molmil
Structure of the AtaT Y144F mutant toxin bound to the C-terminus of the antitoxin AtaR
Descriptor: ACETATE ION, CHLORIDE ION, CITRATE ANION, ...
Authors:Garcia-Pino, A, Jurenas, D.
Deposit date:2018-06-18
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
4WLW
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BU of 4wlw by Molmil
CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA
Descriptor: DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ...
Authors:Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V.
Deposit date:2014-10-08
Release date:2015-09-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
Science, 349, 2015
1UAM
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BU of 1uam by Molmil
Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition
Descriptor: PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase
Authors:Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K.
Deposit date:2003-03-11
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition
EMBO J., 22, 2003
7ZVI
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BU of 7zvi by Molmil
Non-canonical Staphylococcus aureus pathogenicity island repression
Descriptor: Orf22, Sri
Authors:Miguel-Romero, L, Alqasmi, M, Bacarizo, J, Marina, A, Penades, J.R.
Deposit date:2022-05-16
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.973 Å)
Cite:Non-canonical Staphylococcus aureus pathogenicity island repression.
Nucleic Acids Res., 50, 2022
2DTZ
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BU of 2dtz by Molmil
Crystal Structure of multidrug binding protein QacR from Staphylococcus aureus cocrystallized with compound DB75
Descriptor: HTH-type transcriptional regulator qacR, SULFATE ION
Authors:Brooks, B.E, Brennan, R.G.
Deposit date:2006-07-19
Release date:2007-07-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multidrug-Binding Transcription Factor QacR Binds the Bivalent Aromatic Diamidines DB75 and DB359 in Multiple Positions
J.Am.Chem.Soc., 129, 2007
7PWJ
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BU of 7pwj by Molmil
dUTPase from human in complex with Stl
Descriptor: 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ...
Authors:Sanz-Frasquet, C, Marina, A.
Deposit date:2021-10-06
Release date:2022-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases.
Microbiol Spectr, 11, 2023
7F9I
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BU of 7f9i by Molmil
The apo-form structure of EnrR
Descriptor: EnrR repressor
Authors:Gan, J.H, Wang, Q.Y.
Deposit date:2021-07-04
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Xenogeneic nucleoid-associated EnrR thwarts H-NS silencing of bacterial virulence with unique DNA binding.
Nucleic Acids Res., 50, 2022
6E69
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BU of 6e69 by Molmil
Ortho-substituted phenyl sulfonyl fluoride and fluorosulfate as potent elastase inhibitory fragments
Descriptor: 2-(fluorosulfonyl)benzene-1-sulfonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wolan, D.W, Woehl, J.L, Kitamura, S.
Deposit date:2018-07-24
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Proc.Natl.Acad.Sci.USA, 116, 2019
7WQU
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BU of 7wqu by Molmil
FeoC from Klebsiella pneumoniae
Descriptor: Ferrous iron transport protein B, Probable [Fe-S]-dependent transcriptional repressor
Authors:Hsueh, K.L, Yu, L.K, Hsieh, Y.C, Hsiao, Y.Y, Chen, C.J.
Deposit date:2022-01-26
Release date:2023-02-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4.202 Å)
Cite:FeoC from Klebsiella pneumoniae uses its iron sulfur cluster to regulate the GTPase activity of the ferrous iron channel.
Biochim Biophys Acta Proteins Proteom, 1871, 2023
6F5M
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BU of 6f5m by Molmil
Crystal structure of highly glycosylated human leukocyte elastase in complex with a thiazolidinedione inhibitor
Descriptor: 5-[[4-[[(2~{S})-4-methyl-1-oxidanylidene-1-[(2-propylphenyl)amino]pentan-2-yl]carbamoyl]phenyl]methyl]-2-oxidanylidene-1,3-thiazol-1-ium-4-olate, ACETATE ION, Neutrophil elastase, ...
Authors:Hochscherf, J, Pietsch, M, Tieu, W, Kuan, K, Hautmann, S, Abell, A, Guetschow, M, Niefind, K.
Deposit date:2017-12-01
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2' site binding inhibitor.
Acta Crystallogr F Struct Biol Commun, 74, 2018
8BJV
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BU of 8bjv by Molmil
Crystal structure of YopR
Descriptor: GLYCEROL, SPbeta prophage-derived uncharacterized protein YopR
Authors:Gallego del Sol, F, Marina, A.
Deposit date:2022-11-08
Release date:2023-11-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Characterization of a unique repression system present in arbitrium phages of the SPbeta family.
Cell Host Microbe, 31, 2023
8BPZ
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BU of 8bpz by Molmil
Crystal structure of YopR
Descriptor: SPbeta prophage-derived uncharacterized protein YopR
Authors:Gallego del Sol, F, Marina, A.
Deposit date:2022-11-18
Release date:2023-11-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Characterization of a unique repression system present in arbitrium phages of the SPbeta family.
Cell Host Microbe, 31, 2023
8GQE
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BU of 8gqe by Molmil
Crystal structure of the W285A mutant of UVR8 in complex with RUP2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ultraviolet-B receptor UVR8, WD repeat-containing protein RUP2
Authors:Wang, Y.D, Wang, L.X, Guan, Z.Y, chang, H.F, Yin, P.
Deposit date:2022-08-30
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:RUP2 facilitates UVR8 redimerization via two interfaces.
Plant Commun., 4, 2023
8C3K
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BU of 8c3k by Molmil
PaaR2 N-terminal domin in complex with nanobody 33
Descriptor: Nanobody 33, Phage repressor protein CI
Authors:Loris, R, Prolic-Kalinsek, M.
Deposit date:2022-12-26
Release date:2024-01-10
Method:X-RAY DIFFRACTION (1.74972475 Å)
Cite:PaaR2, the CI equivalent in Escherichia coli O157:H7 cryptic prophage CP-933P
To be published
6ON0
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BU of 6on0 by Molmil
STRUCTURE OF N15 CRO COMPLEXED WITH CONSENSUS OPERATOR DNA
Descriptor: DNA (5'-D(*TP*TP*TP*AP*TP*AP*GP*CP*TP*AP*GP*CP*TP*AP*TP*AP*A)-3'), Gp39
Authors:Hall, B.M, Roberts, S.A, Cordes, M.H.J.
Deposit date:2019-04-19
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Extreme divergence between one-to-one orthologs: the structure of N15 Cro bound to operator DNA and its relationship to the lambda Cro complex.
Nucleic Acids Res., 47, 2019
7DLV
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BU of 7dlv by Molmil
shrimp dUTPase in complex with Stl
Descriptor: CALCIUM ION, Orf20, SULFATE ION, ...
Authors:Ma, Q, Wang, F.
Deposit date:2020-11-30
Release date:2021-12-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.525 Å)
Cite:Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase.
Int.J.Biol.Macromol., 184, 2021
8G24
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BU of 8g24 by Molmil
Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin-G, MAP domain-containing protein, ...
Authors:Mishra, N.B, Geisbrecht, B.V.
Deposit date:2023-02-03
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.
J.Biol.Chem., 299, 2023
8G25
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BU of 8g25 by Molmil
Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 7.5
Descriptor: Cathepsin-G, MAP domain-containing protein, Neutrophil elastase
Authors:Mishra, N.B, Geisbrecht, B.V.
Deposit date:2023-02-03
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.
J.Biol.Chem., 299, 2023
8G26
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BU of 8g26 by Molmil
Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 8.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin-G, ...
Authors:Mishra, N.B, Geisbrecht, B.V.
Deposit date:2023-02-03
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.
J.Biol.Chem., 299, 2023
8SLM
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BU of 8slm by Molmil
Crystal structure of Deinococcus geothermalis PprI
Descriptor: MANGANESE (II) ION, SULFATE ION, Zn dependent hydrolase fused to HTH domain, ...
Authors:Zhao, Y, Lu, H.
Deposit date:2023-04-23
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA.
Nat Commun, 15, 2024

224201

數據於2024-08-28公開中

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