1L67
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1L54
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148L
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![BU of 148l by Molmil](/molmil-images/mine/148l) | A COVALENT ENZYME-SUBSTRATE INTERMEDIATE WITH SACCHARIDE DISTORTION IN A MUTANT T4 LYSOZYME | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, BETA-MERCAPTOETHANOL, SUBSTRATE CLEAVED FROM CELL WALL OF ESCHERICHIA COLI, ... | Authors: | Kuroki, R, Weaver, L.H, Matthews, B.W. | Deposit date: | 1993-10-27 | Release date: | 1994-04-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme. Science, 262, 1993
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1LGX
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![BU of 1lgx by Molmil](/molmil-images/mine/1lgx) | T4 Lysozyme Mutant L99A/M102Q Bound by 3,5-difluoroaniline | Descriptor: | 3,5-DIFLUOROANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | Deposit date: | 2002-04-16 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002
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172L
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225L
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![BU of 225l by Molmil](/molmil-images/mine/225l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | Descriptor: | BETA-MERCAPTOETHANOL, PARA-XYLENE, T4 LYSOZYME | Authors: | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | Deposit date: | 1997-06-25 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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233L
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![BU of 233l by Molmil](/molmil-images/mine/233l) | T4 LYSOZYME MUTANT M120L | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W. | Deposit date: | 1997-10-07 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
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1L57
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1QUO
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![BU of 1quo by Molmil](/molmil-images/mine/1quo) | L99A/E108V MUTANT OF T4 LYSOZYME | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME) | Authors: | Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W. | Deposit date: | 1999-07-01 | Release date: | 1999-07-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999
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228L
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![BU of 228l by Molmil](/molmil-images/mine/228l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | Deposit date: | 1997-06-25 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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235L
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![BU of 235l by Molmil](/molmil-images/mine/235l) | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME | Authors: | Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W. | Deposit date: | 1997-10-17 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect. Protein Sci., 7, 1998
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254L
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![BU of 254l by Molmil](/molmil-images/mine/254l) | LYSOZYME | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | Authors: | Kuroki, R, Shoichet, B, Weaver, L.H, Matthews, B.W. | Deposit date: | 1997-11-10 | Release date: | 1998-01-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A relationship between protein stability and protein function. Proc.Natl.Acad.Sci.USA, 92, 1995
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1L70
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![BU of 1l70 by Molmil](/molmil-images/mine/1l70) | |
1L75
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![BU of 1l75 by Molmil](/molmil-images/mine/1l75) | |
223L
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![BU of 223l by Molmil](/molmil-images/mine/223l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | Descriptor: | BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | Deposit date: | 1997-06-25 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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195L
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![BU of 195l by Molmil](/molmil-images/mine/195l) | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | Deposit date: | 1995-11-06 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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1OWZ
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![BU of 1owz by Molmil](/molmil-images/mine/1owz) | T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 4-FluoroPhenEthyl Alcohol | Descriptor: | 4-FLUOROPHENETHYL ALCOHOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | Deposit date: | 2003-03-31 | Release date: | 2004-04-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004
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222L
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![BU of 222l by Molmil](/molmil-images/mine/222l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | Deposit date: | 1997-06-25 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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230L
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![BU of 230l by Molmil](/molmil-images/mine/230l) | T4 LYSOZYME MUTANT M6L | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Lipscomb, L.A, Gassner, N.C, Snow, S, Eldridge, A.M, Drew, D.L, Baase, W.A, Matthews, B.W. | Deposit date: | 1997-10-02 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
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1B6I
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![BU of 1b6i by Molmil](/molmil-images/mine/1b6i) | T4 LYSOZYME MUTANT WITH CYS 54 REPLACED BY THR, CYS 97 REPLACED BY ALA, THR 21 REPLACED BY CYS AND LYS 124 REPLACED BY CYS (C54T,C97A,T21C,K124C) | Descriptor: | 2-HYDROXYETHYL DISULFIDE, PROTEIN (LYSOZYME) | Authors: | Vetter, I.R, Baase, W.A, Snow, S, Matthews, B.W. | Deposit date: | 1999-01-14 | Release date: | 2000-01-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme. Proc.Natl.Acad.Sci.USA, 97, 2000
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2O4W
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![BU of 2o4w by Molmil](/molmil-images/mine/2o4w) | T4 lysozyme circular permutant | Descriptor: | CHLORIDE ION, Lysozyme | Authors: | Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S. | Deposit date: | 2006-12-05 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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1DYA
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1OWY
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![BU of 1owy by Molmil](/molmil-images/mine/1owy) | T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Propyl-Aniline | Descriptor: | 2-PROPYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | Deposit date: | 2003-03-31 | Release date: | 2004-04-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004
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1QTH
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1QT8
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![BU of 1qt8 by Molmil](/molmil-images/mine/1qt8) | T26H Mutant of T4 Lysozyme | Descriptor: | 2-HYDROXYETHYL DISULFIDE, PROTEIN (T4 LYSOZYME) | Authors: | Kuroki, R, Weaver, L.H, Matthews, B.W. | Deposit date: | 1999-06-30 | Release date: | 1999-07-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site. Proc.Natl.Acad.Sci.USA, 96, 1999
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