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PDB: 781 results
3C82
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BU of 3c82 by Molmil
Bacteriophage lysozyme T4 lysozyme mutant K85A/R96H
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:Mooers, B.H.M.
Deposit date:2008-02-08
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
4W57
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BU of 4w57 by Molmil
T4 Lysozyme L99A with n-Butylbenzene Bound
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, N-BUTYLBENZENE
Authors:Merski, M, Shoichet, B.K, Eidam, O, Fischer, M.
Deposit date:2014-08-16
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6801 Å)
Cite:Homologous ligands accommodated by discrete conformations of a buried cavity.
Proc.Natl.Acad.Sci.USA, 112, 2015
6P5W
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BU of 6p5w by Molmil
Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Descriptor: 3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera
Authors:Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A.
Deposit date:2019-05-31
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation.
J.Med.Chem., 62, 2019
4I7S
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BU of 4i7s by Molmil
T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound
Descriptor: 2-HYDROXYETHYL DISULFIDE, 5-methyl-3-(trifluoromethyl)-1H-pyrazole, ACETATE ION, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-11-30
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013
1G0M
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BU of 1g0m by Molmil
CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152I
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
Authors:Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
Deposit date:2000-10-06
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
110L
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BU of 110l by Molmil
STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1992-12-17
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of amino acid alpha helix propensity.
Science, 260, 1993
173L
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BU of 173l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Xiong, X.-P, Zhang, X.-J, Sun, D, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
128L
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BU of 128l by Molmil
THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1993-05-28
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993
129L
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BU of 129l by Molmil
STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Pjura, P, Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
130L
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BU of 130l by Molmil
STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Pjura, P, Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
131L
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BU of 131l by Molmil
STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Pjura, P, Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
138L
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BU of 138l by Molmil
RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Heinz, D.W, Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.
Protein Eng., 7, 1994
139L
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BU of 139l by Molmil
RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Heinz, D.W, Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.
Protein Eng., 7, 1994
2F47
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BU of 2f47 by Molmil
Xray crystal structure of T4 lysozyme mutant L20/R63A liganded to methylguanidinium
Descriptor: 1-METHYLGUANIDINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-22
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
3CDR
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BU of 3cdr by Molmil
R96Q Mutant of wildtype phage T4 lysozyme at 298 K
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme
Authors:Mooers, B.H.M.
Deposit date:2008-02-27
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
1G07
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BU of 1g07 by Molmil
CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149C
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
Authors:Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
Deposit date:2000-10-05
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
161L
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BU of 161l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
1L05
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BU of 1l05 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L62
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BU of 1l62 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
1L11
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BU of 1l11 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L14
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BU of 1l14 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L46
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BU of 1l46 by Molmil
CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
Descriptor: T4 LYSOZYME
Authors:Daopin, S, Matthews, B.W.
Deposit date:1991-01-28
Release date:1991-10-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
J.Mol.Biol., 221, 1991
1L65
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TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Heinz, D, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.
Proc.Natl.Acad.Sci.USA, 89, 1992
1L12
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BU of 1l12 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L16
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BU of 1l16 by Molmil
STRUCTURAL ANALYSIS OF THE TEMPERATURE-SENSITIVE MUTANT OF BACTERIOPHAGE T4 LYSOZYME, GLYCINE 156 (RIGHT ARROW) ASPARTIC ACID
Descriptor: T4 LYSOZYME
Authors:Gray, T.M, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid.
J.Biol.Chem., 262, 1987

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數據於2024-07-31公開中

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