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PDB: 2 results

Structure of I-Ag7 with a bound hybrid insulin peptide
Descriptor:	GLYCEROL, H-2 class II histocompatibility antigen, A-D alpha chain, ...
Authors:	Lopez-Sagaseta, J, Erausquin, E.
Deposit date:	2021-12-13
Release date:	2022-07-20
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.82 Å)
Cite:	Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes. Front Immunol, 13, 2022

Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7.
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4.1 TCR alpha chain, ...
Authors:	Lopez-Sagaseta, J, Erausquin, E.
Deposit date:	2022-03-06
Release date:	2022-07-20
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes. Front Immunol, 13, 2022