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PDB: 1 results

7U8D
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BU of 7u8d by Molmil
FKBP12 mutant V55G bound to Rapa*-3Z
Descriptor: (3S,5Z,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5-(ethoxyimino)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A
Authors:Wassarman, D.R, Shokat, K.M.
Deposit date:2022-03-08
Release date:2022-09-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Tissue-restricted inhibition of mTOR using chemical genetics.
Proc.Natl.Acad.Sci.USA, 119, 2022

227344

數據於2024-11-13公開中

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