8KDN
 
 | | Structure of LAT1-CD98hc in complex with L-Phe, focused on TMD | | Descriptor: | 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, PHENYLALANINE | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDJ
 | | Structure of apo inward-open LAT1-CD98h in nanodisc, focused on TMD | | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4F2 cell-surface antigen heavy chain, CHOLESTEROL, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDH
 | | Structure of LAT1-CD98hc in complex with BCH, focused on TMD | | Descriptor: | (1~{S},2~{R},4~{R})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4F2 cell-surface antigen heavy chain, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDD
 | | Structure of LAT1-CD98hc-Fab170 in complex with JPH203, consensus map | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Fab170 heavy chain, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.83 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDP
 | | Structure of apo outward-open LAT1-CD98h in nanodisc, focused on TMD | | Descriptor: | 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1 | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDI
 | | Structure of apo inward-open LAT1-CD98hc-Fab170 in nanodisc, consensus map | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Fab170 heavy chain, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDF
 | | Structure of LAT1-CD98hc in complex with JPH203, focused on TMD | | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4F2 cell-surface antigen heavy chain, CHOLESTEROL, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDG
 | | Structure of LAT1-CD98hc-Fab170 in complex with BCH, consensus map | | Descriptor: | (1~{S},2~{R},4~{R})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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8KDO
 | | Structure of LAT1-CD98hc in complex with melphalan, focused on TMD | | Descriptor: | (2~{S})-2-azanyl-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid, 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1 | | Authors: | Lee, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structural basis of anticancer drug recognition and amino acid transport by LAT1.
Nat Commun, 16, 2025
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