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PDB: 2 results
6B2Q
Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor:
3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknA
Authors:
Zuccola, H.J.
Deposit date:
2017-09-20
Release date:
2018-02-14
Method:
X-RAY DIFFRACTION (2.88 Å)
Cite:
Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
6B2P
Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor:
5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB
Authors:
Zuccola, H.J.
Deposit date:
2017-09-20
Release date:
2018-02-14
Last modified:
2024-03-13
Method:
X-RAY DIFFRACTION (3.01 Å)
Cite:
Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
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數據於2024-08-14公開中