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Crystal structure of the P2Y12 receptor in complex with the inverse agonist selatogrel.
Descriptor:	CHOLESTEROL, P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, Selatogrel
Authors:	Mac Sweeney, A, Tidten-Luksch, N.
Deposit date:	2021-09-13
Release date:	2022-11-02
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.78 Å)
Cite:	Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation. Biochem Pharmacol, 206, 2022