2CXC
| Crystal structure of archaeal transcription termination factor NusA | Descriptor: | NusA | Authors: | Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-28 | Release date: | 2005-12-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA Biochem.Biophys.Res.Commun., 355, 2007
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2CY1
| Crystal structure of APE1850 | Descriptor: | NusA protein homolog | Authors: | Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-04 | Release date: | 2006-01-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions Acta Crystallogr.,Sect.F, 63, 2007
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1WH9
| Solution structure of the KH domain of human ribosomal protein S3 | Descriptor: | 40S ribosomal protein S3 | Authors: | Nameki, N, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-28 | Release date: | 2004-11-28 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the KH domain of human ribosomal protein S3 To be Published
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5OT7
| Elongation factor G-ribosome complex captures in the absence of inhibitors. | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Mace, K, Giudice, E, Chat, S, Gillet, R. | Deposit date: | 2017-08-21 | Release date: | 2018-02-14 | Last modified: | 2018-04-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors. Nucleic Acids Res., 46, 2018
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5BR8
| Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H. | Deposit date: | 2015-05-29 | Release date: | 2015-11-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin To Be Published
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3T1Y
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. | Deposit date: | 2011-07-22 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416, 2012
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2HHH
| Crystal structure of kasugamycin bound to the 30S ribosomal subunit | Descriptor: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Schluenzen, F. | Deposit date: | 2006-06-28 | Release date: | 2006-09-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat.Struct.Mol.Biol., 13, 2006
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2F4V
| 30S ribosome + designer antibiotic | Descriptor: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ... | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | Deposit date: | 2005-11-24 | Release date: | 2006-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site Chem.Biol., 13, 2006
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3T1H
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin | Descriptor: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. | Deposit date: | 2011-07-21 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416, 2012
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1EGA
| CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA | Descriptor: | PROTEIN (GTP-BINDING PROTEIN ERA), SULFATE ION | Authors: | Chen, X, Ji, X. | Deposit date: | 1998-12-01 | Release date: | 1999-07-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif. Proc.Natl.Acad.Sci.USA, 96, 1999
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1FJG
| STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. | Deposit date: | 2000-08-08 | Release date: | 2000-09-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics Nature, 407, 2000
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6FEC
| Human cap-dependent 48S pre-initiation complex | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Schaffitzel, C, Schaffitzel, C. | Deposit date: | 2017-12-31 | Release date: | 2018-03-14 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
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6FKR
| Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N. | Deposit date: | 2018-01-24 | Release date: | 2018-03-28 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chem Biol, 25, 2018
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3OTO
| Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8) | Descriptor: | 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2010-09-13 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.69 Å) | Cite: | Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function. Rna, 16, 2010
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6G5I
| Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-29 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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2XR1
| DIMERIC ARCHAEAL CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR WITH N-TERMINAL KH DOMAINS (KH-CPSF) FROM METHANOSARCINA MAZEI | Descriptor: | CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT, ZINC ION | Authors: | Mir-Montazeri, B, Ammelburg, M, Forouzan, D, Lupas, A.N, Hartmann, M.D. | Deposit date: | 2010-09-08 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal Structure of a Dimeric Archaeal Cleavage and Polyadenylation Specificity Factor. J.Struct.Biol., 173, 2011
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2ZM6
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Kaminishi, T, Wang, H, Kawazoe, M, Ishii, R, Schluenzen, F, Hanawa-Suetsugu, K, Wilson, D.N, Nomura, M, Takemoto, C, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-04-11 | Release date: | 2009-04-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of the Thermus thermophilus 30S ribosomal subunit To be Published
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3R9X
| Crystal structure of Era in complex with MgGDPNP, nucleotides 1506-1542 of 16S ribosomal RNA, and KsgA | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, GTPase Era, ... | Authors: | Tu, C, Ji, X. | Deposit date: | 2011-03-26 | Release date: | 2011-06-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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2E5L
| A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine- Dalgarno interaction | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Kaminishi, T, Wilson, D.N, Takemoto, C, Harms, J.M, Kawazoe, M, Schluenzen, F, Hanawa-Suetsugu, K, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-21 | Release date: | 2007-05-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction Structure, 15, 2007
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2YKR
| 30S ribosomal subunit with RsgA bound in the presence of GMPPNP | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N. | Deposit date: | 2011-05-30 | Release date: | 2011-08-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy. Proc.Natl.Acad.Sci.USA, 108, 2011
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3R9W
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9BDP
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8Y39
| cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | Deposit date: | 2024-01-28 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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9BDL
| 80S ribosome with angiogenin | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Loveland, A.B, Korostelev, A.A. | Deposit date: | 2024-04-12 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural mechanism of angiogenin activation by the ribosome. Nature, 630, 2024
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9FBV
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