9GR0
 
 | | Interaction with AK2A links AIFM1 to cellular energy metabolism. The cryo-EM structure of dimeric AIFM1 bound by AK2A. | | Descriptor: | Adenylate kinase 2, mitochondrial, Apoptosis-inducing factor 1, ... | | Authors: | Rothemann, R.A, Pavlenko, E.A, Gerlich, S, Grobushkin, P, Mostert, S, Stobbe, D, Racho, J, Stillger, K, Lapacz, K, Petrungaro, C, Dengjel, J, Neundorf, I, Bano, D, Mondal, M, Weiss, K, Ehninger, D, Nguyen, T.H.D, Poepsel, S.P, Riemer, J. | | Deposit date: | 2024-09-10 | | Release date: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Interaction with AK2A links AIFM1 to cellular energy metabolism.
Mol.Cell, 2025
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9CXP
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9C23
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9C25
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9C26
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9FQW
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the ornithine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, High affinity cationic amino acid transporter 1,Green fluorescent protein, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FSC
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9FQU
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FQT
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the apo inward-open state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FQV
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the lysine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, High affinity cationic amino acid transporter 1,Green fluorescent protein, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9O58
 | | Zymogen ADAM17-iRhom2 complex bound by the MEDI3622 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Slone, C.E, Maciag, J.J. | | Deposit date: | 2025-04-09 | | Release date: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural insights into the activation and inhibition of the ADAM17-iRhom2 complex.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9FOS
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8P85
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9MUT
 | | Reduced state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FORMIC ACID, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Last modified: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUV
 | | Oxidized state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, Fluorescent thiol-disulfide redox biosensor, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUU
 | | Oxidized state of a turn-off thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETATE ION, FORMIC ACID, Fluorescent thiol-disulfide redox biosensor, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUS
 | | Reduced state of a turn-off thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETIC ACID, Fluorescent thiol-disulfide redox biosensor, GLYCEROL, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Last modified: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9G33
 | | Stalled 90S - Utp23-Krr1-deltaC3 | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S11-A, ... | | Authors: | Thoms, M, Berninghausen, O, Beckmann, R. | | Deposit date: | 2024-07-11 | | Release date: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | H/ACA snR30 snoRNP guides independent 18S rRNA subdomain formation.
Nat Commun, 16, 2025
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9U3R
 | | Cryo-EM structure of human AC9 | | Descriptor: | Adenylate cyclase type 9,Protein M2-1 | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9U3V
 | | Cryo-EM structure of human AC9_delC (TM domain) | | Descriptor: | Adenylate cyclase type 9,Protein M2-1 | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9U3P
 | | Cryo-EM structure of human AC9-Gs complex (soluble domain) | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 9,Protein M2-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9U3S
 | | Cryo-EM structure of human AC9 (TM domain) | | Descriptor: | Adenylate cyclase type 9,Protein M2-1 | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9U3U
 | | Cryo-EM structure of human AC9_delC | | Descriptor: | Adenylate cyclase type 9,Protein M2-1 | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9U3Q
 | | Cryo-EM structure of human AC9-Gs complex (TM domain) | | Descriptor: | Adenylate cyclase type 9,Protein M2-1 | | Authors: | Suzuki, S, Nomura, R, Suzuki, H, Nishikawa, K, Fujiyoshi, Y. | | Deposit date: | 2025-03-18 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Activation mechanism of human adenylyl cyclase 9 observed by cryo-electron microscopy
To Be Published
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9NPX
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