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PDB: 223790 results
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BIRD
8PO3
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 18 bound to EGFR[V948R]
Descriptor:
2-methyl-5-[[3-[1-[(3~{S})-1-propanoylpyrrolidin-3-yl]-4-pyridin-4-yl-pyrazol-3-yl]phenoxy]methyl]-3~{H}-isoindol-1-one, Epidermal growth factor receptor
Authors:
Hargreaves, D.
Deposit date:
2023-07-03
Release date:
2024-06-05
Last modified:
2024-06-19
Method:
X-RAY DIFFRACTION (2.13 Å)
Cite:
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8R8F
Ensemble-refined carboxymyoglobin photolysis power titration, 6 mJ/cm2
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-29
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R90
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 604 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9H
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 661 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RA3
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 462 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R94
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 1001 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9L
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1036 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RAA
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1023 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R8Z
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 471 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9F
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 537 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R8I
Ensemble-refined carboxymyoglobin photolysis power titration, 56 mJ/cm2
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-29
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RA1
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 312 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R95
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 1401 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RAD
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1235 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9N
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1224 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RA9
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 907 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R8W
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 254 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9E
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 469 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9P
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1297 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RAB
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1112 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R8H
Ensemble-refined carboxymyoglobin photolysis power titration, 31 mJ/cm2
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-29
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R93
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 847 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R9K
Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 922 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8RA4
Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 527 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-12-01
Release date:
2024-01-31
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
8R8X
Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 327 fs time delay
Descriptor:
CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:
Barends, T
,
Schlichting, I.
Deposit date:
2023-11-30
Release date:
2024-03-06
Method:
X-RAY DIFFRACTION (1.4 Å)
Cite:
Influence of pump laser fluence on ultrafast myoglobin structural dynamics.
Nature, 626, 2024
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223790
数据于2024-08-14公开中