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1DCB	STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-03-10 Release date: 1993-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of an engineered His3Cys zinc binding site in human carbonic anhydrase II. Biochemistry, 32, 1993
1DCA	STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1992-12-18 Release date: 1993-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of an engineered His3Cys zinc binding site in human carbonic anhydrase II. Biochemistry, 32, 1993
1CZM	DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I Descriptor: 3-ACTOXYMERCURI-4-AMINOBENZENESULFONAMIDE, CARBONIC ANHYDRASE I, MERCURY (II) ION, ... Authors: Chakravarty, S, Kannan, K.K. Deposit date: 1993-11-28 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243, 1994
1CVH	STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-11-16 Release date: 1995-02-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CVF	STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-06-21 Release date: 1994-11-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CVE	STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-06-21 Release date: 1994-11-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CVD	STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-06-21 Release date: 1994-12-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CVC	REDESIGNING THE ZINC BINDING SITE OF HUMAN CARBONIC ANHYDRASE II: STRUCTURE OF A HIS2ASP-ZN2+ METAL COORDINATION POLYHEDRON Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-09-22 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: REDESIGNING THE ZINC-BINDING SITE OF HUMAN CARBONIC ANHYDRASE-II - STRUCTURE OF A HIS2ASP-ZN2+ METAL COORDINATION POLYHEDRON. J.Am.Chem.Soc., 115, 1993
1CVB	STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-02-04 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II. J.Biol.Chem., 268, 1993
1CVA	STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II Descriptor: AZIDE ION, CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-02-04 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II. J.Biol.Chem., 268, 1993
1CRM	STRUCTURE AND FUNCTION OF CARBONIC ANHYDRASES Descriptor: CARBONIC ANHYDRASE I, CHLORIDE ION, HYDROSULFURIC ACID, ... Authors: Yadava, V.S, Kannan, K.K. Deposit date: 1994-03-04 Release date: 1995-02-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure and Function of Carbonic Anhydrases Biomolecular Structure, Conformation, Function and Evolution, 1, 1981
1CRA	THE COMPLEX BETWEEN HUMAN CARBONIC ANHYDRASE II AND THE AROMATIC INHIBITOR 1,2,4-TRIAZOLE Descriptor: 1,2,4-TRIAZOLE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Mangani, S, Liljas, A. Deposit date: 1992-10-21 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the complex between human carbonic anhydrase II and the aromatic inhibitor 1,2,4-triazole. J.Mol.Biol., 232, 1993
1CNY	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNX	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: AMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNW	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: AMINOMETHYLENECARBONYLAMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNK	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.15 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNJ	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNI	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNH	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNG	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, CHLORIDE ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNC	COMPENSATORY PLASTIC EFFECTS IN THE REDESIGN OF PROTEIN-ZINC BINDING SITES Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-06-13 Release date: 1994-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CNB	COMPENSATORY PLASTIC EFFECTS IN THE REDESIGN OF PROTEIN-ZINC BINDING SITES Descriptor: BETA-MERCAPTOETHANOL, CARBONIC ANHYDRASE II Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1994-06-13 Release date: 1994-10-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural consequences of redesigning a protein-zinc binding site. Biochemistry, 33, 1994
1CIN	THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS Descriptor: (4S-TRANS)-4-(METHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, CARBONIC ANHYDRASE II, METHYL MERCURY ION, ... Authors: Smith, G.M, Alexander, R.S, Christianson, D.W, Mckeever, B.M, Ponticello, G.S, Springer, J.P, Randall, W.C, Baldwin, J.J, Habecker, C.N. Deposit date: 1993-10-20 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci., 3, 1994
1CIM	THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS Descriptor: (4S-TRANS)-4-(AMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO (2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, CARBONIC ANHYDRASE II, METHYL MERCURY ION, ... Authors: Smith, G.M, Alexander, R.S, Christianson, D.W, Mckeever, B.M, Ponticello, G.S, Springer, J.P, Randall, W.C, Baldwin, J.J, Habecker, C.N. Deposit date: 1993-10-20 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci., 3, 1994
1CIL	THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS Descriptor: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, CARBONIC ANHYDRASE II, ZINC ION Authors: Smith, G.M, Alexander, R.S, Christianson, D.W, Mckeever, B.M, Ponticello, G.S, Springer, J.P, Randall, W.C, Baldwin, J.J, Habecker, C.N. Deposit date: 1993-10-20 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci., 3, 1994

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