1PXI
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![BU of 1pxi by Molmil](/molmil-images/mine/1pxi) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-(2,5-Dichloro-thiophen-3-yl)-pyrimidin-2-ylamine | Descriptor: | 4-(2,5-DICHLOROTHIEN-3-YL)PYRIMIDIN-2-AMINE, Cell division protein kinase 2 | Authors: | Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. | Deposit date: | 2003-07-04 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop Structure, 11, 2003
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1PYI
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1PW2
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![BU of 1pw2 by Molmil](/molmil-images/mine/1pw2) | APO STRUCTURE OF HUMAN CYCLIN-DEPENDENT KINASE 2 | Descriptor: | Cell division protein kinase 2 | Authors: | Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. | Deposit date: | 2003-06-30 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the
activation loop. Structure, 11, 2003
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1PPF
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![BU of 1ppf by Molmil](/molmil-images/mine/1ppf) | X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN LEUKOCYTE ELASTASE (PMN ELASTASE) AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR | Descriptor: | HUMAN LEUKOCYTE ELASTASE, TURKEY OVOMUCOID INHIBITOR (OMTKY3), alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bode, W, Wei, A-Z. | Deposit date: | 1991-10-24 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J., 5, 1986
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1Q4L
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![BU of 1q4l by Molmil](/molmil-images/mine/1q4l) | GSK-3 Beta complexed with Inhibitor I-5 | Descriptor: | 2-CHLORO-5-[4-(3-CHLORO-PHENYL)-2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-3-YLAMINO]-BENZOIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. | Deposit date: | 2003-08-04 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333, 2003
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2MSY
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![BU of 2msy by Molmil](/molmil-images/mine/2msy) | Solution structure of Hox homeodomain | Descriptor: | Homeobox protein Hox-C9 | Authors: | Kim, H, Park, S, Han, J, Lee, B. | Deposit date: | 2014-08-11 | Release date: | 2015-09-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding. Biochim.Biophys.Acta, 1854, 2015
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4L85
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2N4T
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2N4S
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2N4W
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2MW9
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1R78
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![BU of 1r78 by Molmil](/molmil-images/mine/1r78) | CDK2 complex with a 4-alkynyl oxindole inhibitor | Descriptor: | 4-((3R,4S,5R)-4-AMINO-3,5-DIHYDROXY-HEX-1-YNYL)-5-FLUORO-3-[1-(3-METHOXY-1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Cell division protein kinase 2 | Authors: | Luk, K.-C, Simcox, M.E, Schutt, A, Rowan, K, Thompson, T, Chen, Y, Kammlott, U, DePinto, W, Dunten, P, Dermatakis, A. | Deposit date: | 2003-10-20 | Release date: | 2004-01-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A new series of potent oxindole inhibitors of CDK2 Bioorg.Med.Chem.Lett., 14, 2004
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1RML
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![BU of 1rml by Molmil](/molmil-images/mine/1rml) | NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE | Authors: | Lozano, R.M, Jimenez, M.A, Santoro, J, Rico, M, Gimenez-Gallego, G. | Deposit date: | 1998-05-21 | Release date: | 1998-11-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas. J.Mol.Biol., 281, 1998
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4KNY
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2N8G
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![BU of 2n8g by Molmil](/molmil-images/mine/2n8g) | NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens | Descriptor: | Homeobox protein GBX-1 | Authors: | Proudfoot, A.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) | Deposit date: | 2015-10-15 | Release date: | 2015-10-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens To be Published
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2N4V
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1PXJ
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![BU of 1pxj by Molmil](/molmil-images/mine/1pxj) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamine | Descriptor: | 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE, Cell division protein kinase 2 | Authors: | Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. | Deposit date: | 2003-07-04 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop Structure, 11, 2003
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1PYE
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![BU of 1pye by Molmil](/molmil-images/mine/1pye) | Crystal structure of CDK2 with inhibitor | Descriptor: | Cell division protein kinase 2, [2-AMINO-6-(2,6-DIFLUORO-BENZOYL)-IMIDAZO[1,2-A]PYRIDIN-3-YL]-PHENYL-METHANONE | Authors: | Zhang, F, Hamdouchi, C. | Deposit date: | 2003-07-08 | Release date: | 2004-07-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines. MOL.CANCER THER., 3, 2004
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2FPU
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![BU of 2fpu by Molmil](/molmil-images/mine/2fpu) | Crystal Structure of the N-terminal domain of E.coli HisB- Complex with histidinol | Descriptor: | CHLORIDE ION, Histidine biosynthesis bifunctional protein hisB, L-histidinol, ... | Authors: | Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2006-01-17 | Release date: | 2006-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
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1PZZ
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![BU of 1pzz by Molmil](/molmil-images/mine/1pzz) | Crystal structure of FGF-1, V51N mutant | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-14 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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2FPX
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![BU of 2fpx by Molmil](/molmil-images/mine/2fpx) | Crystal Structure of the N-terminal Domain of E.coli HisB- Sulfate complex. | Descriptor: | Histidine biosynthesis bifunctional protein hisB, MAGNESIUM ION, SULFATE ION, ... | Authors: | Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2006-01-17 | Release date: | 2006-09-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
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1PKD
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2LSU
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![BU of 2lsu by Molmil](/molmil-images/mine/2lsu) | The NMR high resolution structure of yeast Tah1 in a free form | Descriptor: | TPR repeat-containing protein associated with Hsp90 | Authors: | Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X. | Deposit date: | 2012-05-07 | Release date: | 2013-05-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex. Structure, 21, 2013
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2FPW
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![BU of 2fpw by Molmil](/molmil-images/mine/2fpw) | Crystal Structure of the N-terminal Domain of E.coli HisB- Phosphoaspartate intermediate. | Descriptor: | CALCIUM ION, Histidine biosynthesis bifunctional protein hisB, ZINC ION | Authors: | Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2006-01-17 | Release date: | 2006-09-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. J.Biol.Chem., 281, 2006
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2NTD
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