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7FU1	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-[3-[[(5-bromo-2-hydroxybenzoyl)amino]methyl]phenyl]-2-methylpyrazole-3-carboxylic acid Descriptor: (3P)-3-{3-[(5-bromo-2-hydroxybenzamido)methyl]phenyl}-1-methyl-1H-pyrazole-5-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.074 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUP	Crystal Structure of human cyclic GMP-AMP synthase in complex with methyl 1-benzoyl-3-methyl-5-(1,2-oxazol-5-yl)pyrazole-4-carboxylate Descriptor: Cyclic GMP-AMP synthase, PROPANOIC ACID, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.411 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7K5Z	Crystal Structure of Argininosuccinate synthase from Legionella pneumophila Philadelphia 1 in complex with ANPPNP and a substrate analogue Arginine Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ARGININE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-17 Release date: 2020-09-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of Argininosuccinate synthase from Legionella pneumophila Philadelphia 1 in complex with ANPPNP and a substrate analogue Arginine to be published
5IF9	Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium Descriptor: Cobyrinic Acid a,c-diamide synthase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-25 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium TO BE PUBLISHED
7FTG	Crystal Structure of human cyclic GMP-AMP synthase in complex with cGAMP Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTF	Crystal Structure of apo human cyclic GMP-AMP synthase Descriptor: 1,2-ETHANEDIOL, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.508 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTH	Crystal Structure of human cyclic GMP-AMP synthase in complex with cGAMP Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTK	Crystal Structure of apo human cyclic GMP-AMP synthase Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.125 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTM	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[2-(4-fluoroanilino)-1,3-thiazol-4-yl]acetic acid Descriptor: Cyclic GMP-AMP synthase, ZINC ION, [2-(4-fluoroanilino)-1,3-thiazol-4-yl]acetic acid Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Brunner, M, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTN	Crystal Structure of human cyclic GMP-AMP synthase in complex with propanedioic acid Descriptor: Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*TP*T)-3'), ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Urban, R, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTO	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Zhou, C, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTI	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-(4-fluorophenyl)-2-methylpyrazole-3-carboxylic acid Descriptor: 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-5-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Brunner, M, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTJ	Crystal Structure of apo human cyclic GMP-AMP synthase Descriptor: Cyclic GMP-AMP synthase, POTASSIUM ION, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.461 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTS	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-N-[[2-fluoro-5-(1-methylpyrazol-4-yl)phenyl]methyl]-2-hydroxybenzamide Descriptor: 5-bromo-N-{[(5P)-2-fluoro-5-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-2-hydroxybenzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.215 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTT	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-N-[[2-fluoro-5-(1-methylpyrazol-4-yl)phenyl]methyl]-2-hydroxybenzamide Descriptor: 5-bromo-N-{[(5P)-2-fluoro-5-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-2-hydroxybenzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.235 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTV	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-2-hydroxy-N-(quinolin-6-ylmethyl)benzamide Descriptor: 5-bromo-2-hydroxy-N-[(quinolin-6-yl)methyl]benzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.875 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU0	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-phenylphenyl)methylamino]-5-(trifluoromethyl)-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-{[([1,1'-biphenyl]-4-yl)methyl]amino}-5-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.969 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU2	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Zhou, C, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU3	Crystal Structure of human cyclic GMP-AMP synthase in complex with 8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid Descriptor: (2P)-8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Brunner, M, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.822 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU6	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-benzyl-6-(2-chloro-4-methylphenyl)indazole-4-carboxylic acid Descriptor: (6M)-2-benzyl-6-(2-chloro-4-methylphenyl)-2H-indazole-4-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU8	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.718 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU9	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.668 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUA	Crystal Structure of human cyclic GMP-AMP synthase in complex with phosphate Descriptor: Cyclic GMP-AMP synthase, PHOSPHATE ION, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.444 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUF	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.919 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUG	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.106 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

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