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8DK9
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BU of 8dk9 by Molmil
Sliding-clamp-DinX peptide
Descriptor: ACETYL GROUP, AMINO GROUP, Beta sliding clamp, ...
Authors:Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N.
Deposit date:2022-07-05
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Interaction of sliding clamp with mycobacterial polymerases
To Be Published
8CIX
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BU of 8cix by Molmil
DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin.
Descriptor: ACETATE ION, Beta sliding clamp, CALCIUM ION, ...
Authors:Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R.
Deposit date:2023-02-11
Release date:2023-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
3Q4K
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BU of 3q4k by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
4RKI
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BU of 4rki by Molmil
Crystal structure of sliding beta clamp from Helicobacter pylori
Descriptor: DNA polymerase III subunit beta
Authors:Satyawali, P, Tarique, K.F, Abdul Rehman, S.A, Gourinath, S.
Deposit date:2014-10-13
Release date:2016-01-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into beta-Clamp and its interaction with DNA Ligase in Helicobacter pylori.
Sci Rep, 6, 2016
4TR7
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BU of 4tr7 by Molmil
Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis
Descriptor: DNA polymerase III subunit beta
Authors:Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
Deposit date:2014-06-14
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
4TR8
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BU of 4tr8 by Molmil
Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa
Descriptor: DNA polymerase III subunit beta, SODIUM ION
Authors:Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
Deposit date:2014-06-15
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
3Q4J
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BU of 3q4j by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
4TR6
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BU of 4tr6 by Molmil
Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis
Descriptor: DNA polymerase III subunit beta, SODIUM ION
Authors:Burnouf, D, Olieric, V, Ennifar, E, Wolff, P.
Deposit date:2014-06-14
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
3P16
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BU of 3p16 by Molmil
Crystal structure of DNA polymerase III sliding clamp
Descriptor: DNA polymerase III subunit beta
Authors:Gui, W.J, Lin, S.Q, Chen, Y.Y, Zhang, X.E, Bi, L.J, Jiang, T.
Deposit date:2010-09-30
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis.
Biochem.Biophys.Res.Commun., 405, 2011
4TSZ
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BU of 4tsz by Molmil
Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa with ligand
Descriptor: ACE-GLN-ALC-ASP-LEU-ZCL peptide, DNA polymerase III subunit beta
Authors:Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
Deposit date:2014-06-19
Release date:2014-09-10
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
4S3I
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BU of 4s3i by Molmil
Crystal structure of beta clamp from Helicobacter pylori
Descriptor: DNA polymerase III subunit beta
Authors:Pandey, P, Tarique, K.F, Abdul Rehman, S.A, Gourinath, S.
Deposit date:2015-01-28
Release date:2016-02-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Structural insight into beta-Clamp and its interaction with DNA Ligase in Helicobacter pylori.
Sci Rep, 6, 2016
4TRT
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BU of 4trt by Molmil
Deinococcus radiodurans DNA polymerase III subunit beta
Descriptor: DNA polymerase III subunit beta
Authors:Niiranen, L, Lian, K, Johnson, K.A, Moe, E.
Deposit date:2014-06-17
Release date:2015-04-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the DNA polymerase III beta subunit ( beta-clamp) from the extremophile Deinococcus radiodurans.
Bmc Struct.Biol., 15, 2015
3QSB
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BU of 3qsb by Molmil
Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile
Descriptor: (1R,5R)-5-{(1Z)-N-[(4'-fluorobiphenyl-4-yl)methoxy]butanimidoyl}-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile, DNA polymerase III subunit beta
Authors:Wijffels, G, Johnson, W.M, Oakley, A.J, Turner, K, Epa, V.C, Briscoe, S.J, Polley, M, Liepa, A.J, Hofmann, A, Buchardt, J, Christensen, C, Prosselkov, P, Dalrymple, B.P, Alewood, P.F, Jennings, P.A, Dixon, N.E, Winkler, D.A.
Deposit date:2011-02-20
Release date:2011-06-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Binding inhibitors of the bacterial sliding clamp by design
J.Med.Chem., 54, 2011
3Q4L
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BU of 3q4l by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, SODIUM ION, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
3PWE
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BU of 3pwe by Molmil
Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution
Descriptor: DNA polymerase III subunit beta
Authors:Marzahn, M.R, Robbins, A.H, McKenna, R, Bloom, L.B.
Deposit date:2010-12-08
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:The E. coli clamp loader can actively pry open the beta-sliding clamp
J.Biol.Chem., 286, 2011
3RB9
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BU of 3rb9 by Molmil
Crystal structure of the M. tuberculosis beta clamp
Descriptor: DNA polymerase III subunit beta
Authors:Kukshal, V, Ramachandran, R.
Deposit date:2011-03-29
Release date:2012-04-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase
Plos One, 7, 2012
5FVE
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BU of 5fve by Molmil
Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide
Descriptor: 3,4-difluorobenzamide, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-02-05
Release date:2017-02-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
5G48
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BU of 5g48 by Molmil
H.pylori Beta clamp in complex with Diflunisal
Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-05-06
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal.
FEBS Lett., 591, 2017
5FXT
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BU of 5fxt by Molmil
Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen
Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, DNA POLYMERASE III SUBUNIT BETA
Authors:Pandey, P, Gourinath, S.
Deposit date:2016-03-02
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
8VAP
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BU of 8vap by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAR
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BU of 8var by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAL
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BU of 8val by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAQ
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BU of 8vaq by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAS
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BU of 8vas by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAN
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BU of 8van by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation
Descriptor: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
Authors:Landeck, J.T, Pajak, J, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024

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数据于2024-09-11公开中

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