PDB: 66833 resultsInfo pagesStatus searchChemie searchBIRD

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4HOD	Crystal structure of LeuT-E290S with bound Cl Descriptor: CHLORIDE ION, LEUCINE, SODIUM ION, ... Authors: Kantcheva, A.K, Quick, M, Shi, L, Winther, A.M.L, Stolzenberg, S, Weinstein, H, Javitch, J.A, Nissen, P. Deposit date: 2012-10-22 Release date: 2013-05-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The chloride binding site of Neurotransmitter Sodium Symporters Proc.Natl.Acad.Sci.USA, 2013
4HW5	Crystal Structure of the Human C3a anaphylatoxin Descriptor: Complement C3, SULFATE ION Authors: Bajic, G, Yatime, L, Andersen, G.R. Deposit date: 2012-11-07 Release date: 2012-12-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg. Protein Sci., 22, 2013
4KYN	Crystal structure of odorant binding protein 48 from Anopheles gambiae at 3.3 Angstrom resolution Descriptor: Odorant binding protein-8 Authors: Tsitsanou, K.E, Drakou, C.E, Zographos, S.E. Deposit date: 2013-05-29 Release date: 2013-10-16 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal and Solution Studies of the "Plus-C" Odorant-binding Protein 48 from Anopheles gambiae: CONTROL OF BINDING SPECIFICITY THROUGH THREE-DIMENSIONAL DOMAIN SWAPPING. J.Biol.Chem., 288, 2013
3MH1	Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-04-07 Release date: 2010-04-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
3N4D	Crystal structure of Cg10062 inactivated by(R)-oxirane-2-carboxylate Descriptor: Putative tautomerase Authors: Guo, Y, Robertson, B.A, Hackert, M.L, Whitman, C.P. Deposit date: 2010-05-21 Release date: 2011-06-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Crystal Structures of the Native and Inactivated Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase from Corynebacterium glutamicum: Implications for the Evolution of cis-3-Chloroacrylic Acid Dehalogenase Activity in the Tautomerase Superfamily To be Published
4M4L	The structure of Cu T6 bovine insulin Descriptor: COPPER (II) ION, Insulin Authors: Frankaer, C.G, Harris, P, Stahl, K. Deposit date: 2013-08-07 Release date: 2014-01-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
3NNX	Crystal structure of phosphorylated P38 alpha in complex with DP802 Descriptor: 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide, Mitogen-activated protein kinase 14 Authors: Abendroth, J. Deposit date: 2010-06-24 Release date: 2010-09-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
3NNV	Crystal structure of P38 alpha in complex with DP437 Descriptor: 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-3-naphthalen-1-ylurea, Mitogen-activated protein kinase 14 Authors: Abendroth, J. Deposit date: 2010-06-24 Release date: 2010-09-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
3NYK	The structure of cobalt-substituted pseudoazurin from Alcaligenes faecalis Descriptor: COBALT (II) ION, Pseudoazurin Authors: Gessmann, R, Petratos, K. Deposit date: 2010-07-15 Release date: 2010-10-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.86 Å) Cite: The crystal structure of cobalt-substituted pseudoazurin from Alcaligenes faecalis. Biopolymers, 95, 2011
4MIH	Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant H158A mutant Descriptor: 3-deoxy-3-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase Authors: Hassan, N, Tan, T.C, Spadiut, O, Pisanelli, I, Fusco, L, Haltrich, D, Peterbauer, C, Divne, C. Deposit date: 2013-08-31 Release date: 2013-12-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of Phanerochaete chrysosporium pyranose 2-oxidase suggest that the N-terminus acts as a propeptide that assists in homotetramer assembly. FEBS Open Bio, 3, 2013
3O8U	Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding Descriptor: 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-08-03 Release date: 2010-09-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
3O8P	Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding Descriptor: 1,2-ETHANEDIOL, 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14, ... Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-08-03 Release date: 2010-09-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
3OC1	Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding Descriptor: 1,2-ETHANEDIOL, 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14 Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-08-09 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
3O8T	Conformational plasticity of p38 MAP kinase DFG-motif mutants in response to inhibitor binding Descriptor: 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-08-03 Release date: 2010-11-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
3OBG	Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding Descriptor: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, Mitogen-activated protein kinase 14 Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-08-06 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
3OV1	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide Descriptor: FORMIC ACID, GLYCEROL, Growth factor receptor-bound protein 2, ... Authors: Clements, J.H, Martin, S.F. Deposit date: 2010-09-15 Release date: 2011-11-02 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
4LP4	Crystal structure of the human RAGE VC1 fragment in space group P62 Descriptor: Advanced glycosylation end product-specific receptor, SODIUM ION Authors: Yatime, L, Andersen, G.R. Deposit date: 2013-07-15 Release date: 2013-10-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products. Febs J., 280, 2013
3OVE	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide Descriptor: CHLORIDE ION, Growth factor receptor-bound protein 2, PYAC7CN Authors: Clements, J.H, Martin, S.F. Deposit date: 2010-09-16 Release date: 2011-11-02 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
4LBW	Identifying ligand binding hot spots in proteins using brominated fragments Descriptor: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ... Authors: Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P. Deposit date: 2013-06-21 Release date: 2013-09-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.741 Å) Cite: Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69, 2013
3MPA	Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding Descriptor: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. Deposit date: 2010-04-26 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding TO BE PUBLISHED
3P7F	Structure of the human Langerin carbohydrate recognition domain Descriptor: C-type lectin domain family 4 member K, CALCIUM ION Authors: Skerra, A, Schiefner, A. Deposit date: 2010-10-12 Release date: 2010-11-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site. Mol.Immunol., 45, 2008
4M4M	The structure of Ni T6 bovine insulin Descriptor: Insulin, NICKEL (II) ION Authors: Frankaer, C.G, Harris, P, Stahl, K. Deposit date: 2013-08-07 Release date: 2014-01-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
3PG3	Human p38 MAP Kinase in Complex with RL182 Descriptor: 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(pyridin-3-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. Deposit date: 2010-10-29 Release date: 2011-11-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-based design and synthesis of cell active N-pyrazole, N-thiazole urea inhibitors of the MAP kinase p38alpha To be Published
4NWD	Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid at 2.6 A resolution Descriptor: (4R)-4-[3-(methylamino)-3-oxopropyl]-L-glutamic acid, CHLORIDE ION, Glutamate receptor ionotropic, ... Authors: Venskutonyte, R, Larsen, A.P, Frydenvang, K, Gajhede, M, Kastrup, J.S. Deposit date: 2013-12-06 Release date: 2014-08-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular Recognition of Two 2,4-syn-Functionalized (S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain. Chemmedchem, 9, 2014
4NZD	Interleukin 21 receptor Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-21 receptor, ... Authors: Hamming, O.T, Kang, L, Siupka, P, Gad, H.H, Hartmann, R. Deposit date: 2013-12-12 Release date: 2014-12-17 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Interleukin 21 receptor structure and function To be Published

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