7Y5A
 
 | | Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Wong, C.F, Saw, W.-G, Grueber, G. | | Deposit date: | 2022-06-16 | | Release date: | 2022-11-23 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
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8SPW
 | | PS3 F1 Rotorless, low ATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | | Authors: | Sobti, M, Stewart, A.G. | | Deposit date: | 2023-05-03 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The series of conformational states adopted by rotorless F 1 -ATPase during its hydrolysis cycle.
Structure, 32, 2024
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8F39
 | | Yeast ATP synthase in conformation-2, at pH 6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | Deposit date: | 2022-11-09 | | Release date: | 2024-02-07 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
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8HHB
 | | F1 domain of FoF1-ATPase from Bacillus PS3,step waiting,lowATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-11-16 | | Release date: | 2023-07-19 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
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6LY8
 | | V/A-ATPase from Thermus thermophilus, the soluble domain, including V1, d, two EG stalks, and N-terminal domain of a-subunit. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | Authors: | Kishikawa, J, Nakanishi, A, Furuta, A, Kato, T, Namba, K, Tamakoshi, M, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2020-02-13 | | Release date: | 2020-09-09 | | Last modified: | 2020-09-30 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Mechanical inhibition of isolated V o from V/A-ATPase for proton conductance.
Elife, 9, 2020
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5FL7
 | | Structure of the F1c10 complex from Yarrowia lipolytica ATP synthase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP SYNTHASE DELTA CHAIN, ... | | Authors: | Parey, K, Bublitz, M, Meier, T. | | Deposit date: | 2015-10-22 | | Release date: | 2016-06-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology.
Mol.Cell, 63, 2016
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7JG7
 | | Cryo-EM structure of bedaquiline-free Mycobacterium smegmatis ATP synthase rotational state 3 (backbone model) | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | Authors: | Guo, H, Courbon, G.M, Rubinstein, J.L. | | Deposit date: | 2020-07-18 | | Release date: | 2020-08-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Nature, 589, 2021
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8DBS
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6RDZ
 | | Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, composite map | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | | Authors: | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | | Deposit date: | 2019-04-12 | | Release date: | 2019-07-03 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
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8APC
 | | rotational state 1c of the Trypanosoma brucei mitochondrial ATP synthase dimer | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | Authors: | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | Deposit date: | 2022-08-09 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APG
 | | rotational state 2b of the Trypanosoma brucei mitochondrial ATP synthase dimer | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | Authors: | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | Deposit date: | 2022-08-09 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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7TMM
 | | Complete V1 Complex from Saccharomyces cerevisiae | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-ATPase subunit E, ... | | Authors: | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | Deposit date: | 2022-01-19 | | Release date: | 2022-04-06 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TMR
 | | V-ATPase from Saccharomyces cerevisiae, State 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ... | | Authors: | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | Deposit date: | 2022-01-19 | | Release date: | 2022-04-13 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7U8O
 | | Structure of porcine V-ATPase with mEAK7 and SidK, Rotary state 2 | | Descriptor: | ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, Bacterial effector protein SidK, ... | | Authors: | Tan, Y.Z, Keon, K.A. | | Deposit date: | 2022-03-09 | | Release date: | 2022-07-06 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
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3FKS
 | | Yeast F1 ATPase in the absence of bound nucleotides | | Descriptor: | ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ... | | Authors: | Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M. | | Deposit date: | 2008-12-17 | | Release date: | 2009-03-03 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.587 Å) | | Cite: | Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides.
J.Biol.Chem., 284, 2009
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9BRB
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6Q45
 | | F1-ATPase from Fusobacterium nucleatum | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Petri, J, Nakatani, Y, Montgomery, M.G, Ferguson, S.A, Aragao, D, Leslie, A.G.W, Heikal, A, Walker, J.E, Cook, G.M. | | Deposit date: | 2018-12-05 | | Release date: | 2019-07-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum.
Open Biology, 9, 2019
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6R0W
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6RE0
 | | Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, monomer-masked refinement | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | | Authors: | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | | Deposit date: | 2019-04-12 | | Release date: | 2019-07-03 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
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8HH9
 | | F1 domain of FoF1-ATPase from Bacillus PS3, 90 degrees, low ATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-11-16 | | Release date: | 2023-07-19 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
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7NKK
 | | Mycobacterium smegmatis ATP synthase rotor state 2 | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6B8H
 | | Mosaic model of yeast mitochondrial ATP synthase monomer | | Descriptor: | AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ... | | Authors: | Guo, H, Bueler, S.A, Rubinstein, J.L. | | Deposit date: | 2017-10-07 | | Release date: | 2018-01-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Atomic model for the dimeric FO region of mitochondrial ATP synthase.
Science, 358, 2017
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8DBP
 | | E. coli ATP synthase imaged in 10mM MgATP State1 "half-up | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Sobti, M, Stewart, A.G. | | Deposit date: | 2022-06-14 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Changes within the central stalk of E. coli F 1 F o ATP synthase observed after addition of ATP.
Commun Biol, 6, 2023
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6VQ9
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6VQB
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