3DBO
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![BU of 3dbo by Molmil](/molmil-images/mine/3dbo) | Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... | Authors: | Miallau, L, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2008-06-02 | Release date: | 2008-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems: VapBC-5 FROM MYCOBACTERIUM TUBERCULOSIS. J.Biol.Chem., 284, 2009
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6A7V
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![BU of 6a7v by Molmil](/molmil-images/mine/6a7v) | Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex | Descriptor: | Antitoxin VapB11, PENTAETHYLENE GLYCOL, Ribonuclease VapC11, ... | Authors: | Deep, A, Thakur, K.G. | Deposit date: | 2018-07-04 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation. Nucleic Acids Res., 46, 2018
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4XGQ
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![BU of 4xgq by Molmil](/molmil-images/mine/4xgq) | Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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4XGR
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![BU of 4xgr by Molmil](/molmil-images/mine/4xgr) | Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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3ZVK
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![BU of 3zvk by Molmil](/molmil-images/mine/3zvk) | Crystal structure of VapBC2 from Rickettsia felis bound to a DNA fragment from their promoter | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB, DNA, ... | Authors: | Mate, M.J, Ortiz-Lombardia, M, Cambillau, C. | Deposit date: | 2011-07-25 | Release date: | 2011-12-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the DNA-Bound Vapbc2 Antitoxin/Toxin Pair from Rickettsia Felis. Nucleic Acids Res., 40, 2012
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7BY2
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![BU of 7by2 by Molmil](/molmil-images/mine/7by2) | |
7BY3
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![BU of 7by3 by Molmil](/molmil-images/mine/7by3) | Toxin-antitoxin complex from klebsiella pneumoniae | Descriptor: | CopG family transcriptional regulator, Ribonuclease VapC, SULFATE ION | Authors: | Kang, S.M. | Deposit date: | 2020-04-21 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Toxin-antitoxin complex from klebsiella pneumoniae To Be Published
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4CHG
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![BU of 4chg by Molmil](/molmil-images/mine/4chg) | Crystal structure of VapBC15 complex from Mycobacterium tuberculosis | Descriptor: | ANTITOXIN VAPB15, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Das, U, Pogenberg, V, Tiruttani Subhramanyam, U.K, Wilmanns, M, Srinivasan, A, Gourinath, S. | Deposit date: | 2013-12-02 | Release date: | 2014-11-12 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Vapbc-15 Complex from Mycobacterium Tuberculosis Reveals a Two-Metal Ion Dependent Pin-Domain Ribonuclease And a Variable Mode of Toxin-Antitoxin Assembly. J.Struct.Biol., 188, 2014
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2H1O
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![BU of 2h1o by Molmil](/molmil-images/mine/2h1o) | Structure of FitAB bound to IR36 DNA fragment | Descriptor: | IR36-strand 1, IR36-strand 2, Trafficking protein A, ... | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | Deposit date: | 2006-05-16 | Release date: | 2006-09-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. J.Biol.Chem., 281, 2006
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3H87
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![BU of 3h87 by Molmil](/molmil-images/mine/3h87) | Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, IMIDAZOLE, ... | Authors: | Min, A, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2009-04-28 | Release date: | 2009-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site. Protein Sci., 21, 2012
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5X3T
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![BU of 5x3t by Molmil](/molmil-images/mine/5x3t) | VapBC from Mycobacterium tuberculosis | Descriptor: | Antitoxin VapB26, MAGNESIUM ION, Ribonuclease VapC26 | Authors: | Kang, S.M, Kim, D.H, Yoon, H.J, Lee, B.J. | Deposit date: | 2017-02-07 | Release date: | 2017-06-07 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides. Nucleic Acids Res., 45, 2017
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