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PDB: 873 results

1L64
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TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Heinz, D, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.
Proc.Natl.Acad.Sci.USA, 89, 1992
1L76
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TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Sauer, U, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions.
J.Biol.Chem., 267, 1992
1G0G
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BU of 1g0g by Molmil
CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152A
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
Authors:Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
Deposit date:2000-10-06
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
1G1V
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BU of 1g1v by Molmil
T4 LYSOZYME MUTANT C54T/C97A/I58T
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Quillin, M.L, Matthews, B.W.
Deposit date:2000-10-13
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
195L
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BU of 195l by Molmil
THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W.
Deposit date:1995-11-06
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
148L
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BU of 148l by Molmil
A COVALENT ENZYME-SUBSTRATE INTERMEDIATE WITH SACCHARIDE DISTORTION IN A MUTANT T4 LYSOZYME
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, BETA-MERCAPTOETHANOL, SUBSTRATE CLEAVED FROM CELL WALL OF ESCHERICHIA COLI, ...
Authors:Kuroki, R, Weaver, L.H, Matthews, B.W.
Deposit date:1993-10-27
Release date:1994-04-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme.
Science, 262, 1993
172L
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PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Weaver, L.H, Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
1PQJ
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T4 LYSOZYME CORE REPACKING MUTANT A111V/CORE10/TA
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme, ...
Authors:Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W.
Deposit date:2003-06-18
Release date:2003-10-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:REPACKING THE CORE OF T4 LYSOZYME BY AUTOMATED DESIGN
J.Mol.Biol., 332, 2003
2O4W
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BU of 2o4w by Molmil
T4 lysozyme circular permutant
Descriptor: CHLORIDE ION, Lysozyme
Authors:Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S.
Deposit date:2006-12-05
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment.
Protein Sci., 16, 2007
1B6I
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T4 LYSOZYME MUTANT WITH CYS 54 REPLACED BY THR, CYS 97 REPLACED BY ALA, THR 21 REPLACED BY CYS AND LYS 124 REPLACED BY CYS (C54T,C97A,T21C,K124C)
Descriptor: 2-HYDROXYETHYL DISULFIDE, PROTEIN (LYSOZYME)
Authors:Vetter, I.R, Baase, W.A, Snow, S, Matthews, B.W.
Deposit date:1999-01-14
Release date:2000-01-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme.
Proc.Natl.Acad.Sci.USA, 97, 2000
1OWZ
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T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 4-FluoroPhenEthyl Alcohol
Descriptor: 4-FLUOROPHENETHYL ALCOHOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-31
Release date:2004-04-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1JTM
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Alternative Structures of a Sequence Extended T4 Lysozyme Show that the Highly Conserved Beta-Sheet has Weak Intrinsic Folding Propensity
Descriptor: BETA-MERCAPTOETHANOL, LYSOZYME
Authors:Sagermann, M, Matthews, B.W.
Deposit date:2001-08-21
Release date:2002-03-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of a T4-lysozyme Duplication-extension Mutant Demonstrate that the Highly Conserved beta-Sheet Region has Low Intrinsic Folding Propensity
J.Mol.Biol., 316, 2002
1D9W
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BACTERIOPHAGE T4 LYSOZYME MUTANT
Descriptor: BETA-MERCAPTOETHANOL, PROTEIN (LYSOZYME)
Authors:Korndoerfer, I.P, Matthews, B.W.
Deposit date:1999-10-30
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Helix Capping in Bacteriophage T4 Lysozyme
To be Published
259L
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BU of 259l by Molmil
AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME
Descriptor: CHLORIDE ION, COBALT (II) ION, PROTEIN (LYSOZYME)
Authors:Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W.
Deposit date:1999-02-10
Release date:1999-04-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site.
Protein Eng., 13, 2000
2OU0
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BU of 2ou0 by Molmil
1-methylpyrrole in complex with T4 Lysozyme L99A
Descriptor: 1-METHYL-1H-PYRROLE, Lysozyme, PHOSPHATE ION
Authors:Graves, A.P, Shoichet, B.K.
Deposit date:2007-02-09
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Predicting absolute ligand binding free energies to a simple model site.
J.Mol.Biol., 371, 2007
1CX7
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BU of 1cx7 by Molmil
T4 LYSOZYME METHIONINE CORE MUTANT
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
Authors:Gassner, N.C, Baase, W.A, Lindstrom, J, Lu, J, Matthews, B.W.
Deposit date:1999-08-28
Release date:1999-11-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Use of differentially substituted selenomethionine proteins in X-ray structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
3C7Y
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BU of 3c7y by Molmil
Mutant R96A OF T4 lysozyme in wildtype background at 298K
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, lysozyme
Authors:Mooers, B.H.M.
Deposit date:2008-02-08
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
200L
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BU of 200l by Molmil
THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W.
Deposit date:1995-11-06
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
1L99
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BU of 1l99 by Molmil
PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W.
Deposit date:1992-07-13
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1OVH
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BU of 1ovh by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Chloro-6-Methyl-Aniline
Descriptor: 2-CHLORO-6-METHYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-26
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
191L
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A HELIX INITIATION SIGNAL IN T4 LYSOZYME IDENTIFIED BY POLYALANINE MUTAGENESIS
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis.
Biophys.Chem., 101-102, 2002
6U0B
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BU of 6u0b by Molmil
Neutron crystal structure of wtT4LD
Descriptor: CHLORIDE ION, Endolysin
Authors:Cuneo, M.J, Myles, D.A, Li, L.
Deposit date:2019-08-14
Release date:2020-08-19
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (1.951 Å), X-RAY DIFFRACTION
Cite:Solvent entry into cavities of T4 lysozyme.
To be published
6IIH
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BU of 6iih by Molmil
crystal structure of mitochondrial calcium uptake 2(MICU2)
Descriptor: CALCIUM ION, Endolysin,Calcium uptake protein 2, mitochondrial
Authors:Shen, Q, Wu, W, Zheng, J, Jia, Z.
Deposit date:2018-10-06
Release date:2019-08-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.958 Å)
Cite:The crystal structure of MICU2 provides insight into Ca2+binding and MICU1-MICU2 heterodimer formation.
Embo Rep., 20, 2019
215L
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BU of 215l by Molmil
PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME
Descriptor: 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME
Authors:Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W.
Deposit date:1996-09-23
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme.
Protein Sci., 5, 1996
1D3J
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BU of 1d3j by Molmil
N-TERMINAL DOMAIN CORE METHIONINE MUTATION
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
Authors:Gassner, N.C, Matthews, B.W.
Deposit date:1999-09-29
Release date:1999-10-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Use of differentially substituted selenomethionine proteins in X-ray structure determination.
Acta Crystallogr.,Sect.D, 55, 1999

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数据于2024-09-11公开中

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