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PDB: 1 results

6P6V
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BU of 6p6v by Molmil
HCV NS3/4A protease domain of genotype 5a in complex with glecaprevir
Descriptor: (3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17, 3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide, 1,2-ETHANEDIOL, ...
Authors:Timm, J, Schiffer, C.A.
Deposit date:2019-06-04
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir and characterization of genotype-specific structural differences
To Be Published

222415

数据于2024-07-10公开中

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