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PDB: 11 results
2BIO
human p53 core domain mutant M133L-V203A-N239Y-R249S-N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2005-01-25
Release date:
2005-01-26
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.9 Å)
Cite:
Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIQ
human p53 core domain mutant T123A-M133L-H168R-V203A-N239Y-R249S- N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2005-01-25
Release date:
2005-01-26
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIP
human p53 core domain mutant M133L-H168R-V203A-N239Y-R249S-N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2005-01-25
Release date:
2005-01-26
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIN
human p53 core domain mutant M133L-H168R-V203A-N239Y-N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2005-01-25
Release date:
2005-01-26
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.9 Å)
Cite:
Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIM
human p53 core domain mutant M133L-V203A-N239Y-N268D-R273H
Descriptor:
CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2005-01-25
Release date:
2005-01-26
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.98 Å)
Cite:
Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2J1Z
Human p53 core domain mutant M133L-V203A-N239Y-N268D-F270L
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J21
Human p53 core domain mutant M133L-V203A-N239Y-N268D-R282W
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.6 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J1Y
Human p53 core domain mutant M133L-V203A-N239Y-G245S-N268D
Descriptor:
CALCIUM ION, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.69 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J20
Human p53 core domain mutant M133L-V203A-N239Y-N268D-R273C
Descriptor:
CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
Authors:
Joerger, A.C
,
Ang, H.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J1X
Human p53 core domain mutant M133L-V203A-Y220C-N239Y-N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.65 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J1W
Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D
Descriptor:
CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:
Joerger, A.C
,
Fersht, A.R.
Deposit date:
2006-08-15
Release date:
2006-09-20
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
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数据于2024-10-09公开中