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PDB: 1 results
7RTP
Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
Descriptor:
JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
Authors:
Yan, N.L
,
Wilson, I.A
,
Kelly, J.W.
Deposit date:
2021-08-13
Release date:
2022-02-16
Last modified:
2024-10-30
Method:
X-RAY DIFFRACTION (2.09 Å)
Cite:
Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Bioorg.Med.Chem.Lett., 60, 2022
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数据于2024-11-13公开中