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Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile
Descriptor:	(2R)-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamide, Mitogen-activated protein kinase kinase kinase 5
Authors:	Dougan, D.R.
Deposit date:	2020-06-19
Release date:	2020-08-12
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3character and an exquisite selectivity profile. Bioorg.Med.Chem.Lett., 30, 2020