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3F8S
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Crystal structure of dipeptidyl peptidase IV in complex with inhibitor
Descriptor: 2-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ammirati, M.J, Liu, S, Piotrowski, D.W.
Deposit date:2008-11-13
Release date:2009-06-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor.
Bioorg.Med.Chem.Lett., 19, 2009

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数据于2024-11-06公开中

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