PDB: 54422 resultsInfo pagesStatus searchChemie searchBIRD

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6SZF	Solution structure of the amyloid beta-peptide (1-42) Descriptor: Amyloid-beta precursor protein Authors: Grimaldi, M, Santoro, A, Stillitano, I, Buonocore, M, D'Ursi, A.M. Deposit date: 2019-10-02 Release date: 2020-10-14 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Exploring the Early Stages of the Amyloid A beta (1-42) Peptide Aggregation Process: An NMR Study. Pharmaceuticals, 14, 2021
6LNZ	NMR solution structure of VEGF G-quadruplex bound a non-planar cyclometalated-carbene platinum(II) complex Descriptor: DNA (5'-D(*CP*GP*GP*GP*GP*CP*GP*GP*GP*CP*CP*TP*TP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), cyclometalated-carbene platinum(II) complex Authors: Liu, W, Zhu, B.Z, Mao, Z.W. Deposit date: 2020-01-02 Release date: 2021-01-13 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Selectivity and Targeting of G-Quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics. Angew.Chem.Int.Ed.Engl., 60, 2021
6LUK	Crystal structure of the SAMD1 SAM domain in another crystal form Descriptor: Atherin, SULFATE ION Authors: Cao, Y, Zhou, Y, Wang, Z. Deposit date: 2020-01-29 Release date: 2021-02-03 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.054 Å) Cite: The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
6TAZ	Timeless couples G quadruplex detection with processing by DDX11 during DNA replication Descriptor: Protein timeless homolog Authors: Lerner Koch, L, Holzer, S, Kilkenny, M.L, Murat, P, Svikovic, S, Schiavone, D, Bittleston, A, Maman, J.D, Branzei, D, Stott, K, Pellegrini, L, Sale, E.J. Deposit date: 2019-10-31 Release date: 2020-07-01 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication. Embo J., 39, 2020
5QYB	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a Descriptor: (3-methoxyphenyl)(pyrrolidin-1-yl)methanone, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYA	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D02a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY9	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C11b Descriptor: A1 cistron-splicing factor AAR2, N-ethyl-N-(thiophene-2-carbonyl)-beta-alanine, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY8	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C10a Descriptor: 1,3-benzodioxole-5-carbothioamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.59 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYC	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D07a Descriptor: 2-fluoranyl-~{N}-(furan-2-ylmethyl)benzenesulfonamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYD	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E05a Descriptor: 2-(2-methylphenyl)acetamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYE	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E12a Descriptor: (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYF	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry F02a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.49 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYG	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry F08a Descriptor: 4-[(methylamino)methyl]phenol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYL	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 01 Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
1FU2	FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA Descriptor: CHLORIDE ION, INSULIN, A CHAIN, ... Authors: Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. Deposit date: 2000-09-13 Release date: 2000-10-16 Last modified: 2024-11-13 Method: POWDER DIFFRACTION Cite: The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
6CPT	crystal structure of yeast caPDE2 in complex with IBMX Descriptor: 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, Phosphodiesterase, ... Authors: Ke, h, Wang, Y. Deposit date: 2018-03-14 Release date: 2019-02-20 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structures of Candida albicans Phosphodiesterase 2 and Implications for Its Biological Functions. Biochemistry, 57, 2018
2F35	Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... Authors: Mayer, M.L. Deposit date: 2005-11-18 Release date: 2006-04-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006
3TDJ	Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-97 at 1.95 A resolution Descriptor: 4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, CHLORIDE ION, GLUTAMIC ACID, ... Authors: Krintel, C, Frydenvang, K, Gajhede, M, Kastrup, J.S. Deposit date: 2011-08-11 Release date: 2011-09-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem.J., 441, 2012
6IWS	Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein Descriptor: DnaJ homolog subfamily A member 3, mitochondrial Authors: Sim, D.W, Jo, K.S, Won, H.S, Kim, J.H. Deposit date: 2018-12-06 Release date: 2019-12-11 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein To Be Published
6D3S	Thermostabilized phosphorylated chicken CFTR Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator Authors: Fay, J.F, Riordan, J.R, Chen, Z.J. Deposit date: 2018-04-16 Release date: 2018-10-17 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. Biochemistry, 57, 2018
1EOT	SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE Descriptor: EOTAXIN Authors: Crump, M.P, Rajarathnam, K, Sykes, B.D. Deposit date: 1998-06-17 Release date: 1999-01-13 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J.Biol.Chem., 273, 1998
5QYM	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 02 Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.47 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYK	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry H12a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYH	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry G04a Descriptor: A1 cistron-splicing factor AAR2, N-(4-methoxyphenyl)acetamide, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.47 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYT	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 09 Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.52 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020

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