5L3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l3v by Molmil](/molmil-images/mine/5l3v) | Structure of the crenarchaeal SRP54 GTPase bound to GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle 54 kDa protein | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
|
|
8UOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uob by Molmil](/molmil-images/mine/8uob) | SARS-CoV-2 Papain-like protease (PLpro) with Inhibitor Jun12682 | Descriptor: | 5-[2-(dimethylamino)ethoxy]-N-{(1R)-1-[(3M,5P)-3-(1-ethyl-1H-pyrazol-3-yl)-5-(1-methyl-1H-pyrazol-4-yl)phenyl]ethyl}-2-methylbenzamide, CHLORIDE ION, Papain-like protease nsp3, ... | Authors: | Ansari, A, Tan, B, Ruiz, F.X, Wang, J, Arnold, E. | Deposit date: | 2023-10-19 | Release date: | 2024-04-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science, 383, 2024
|
|
7S24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7s24 by Molmil](/molmil-images/mine/7s24) | Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL | Authors: | Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R. | Deposit date: | 2021-09-03 | Release date: | 2022-08-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing. Nat Commun, 13, 2022
|
|
5L3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l3s by Molmil](/molmil-images/mine/5l3s) | Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
|
|
5IIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iit by Molmil](/molmil-images/mine/5iit) | |
7ZOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zoa by Molmil](/molmil-images/mine/7zoa) | cryo-EM structure of CGT ABC transporter in presence of CBG substrate | Descriptor: | Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, Cyclooctadecakis-(1-2)-(beta-D-glucopyranose) | Authors: | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | Deposit date: | 2022-04-24 | Release date: | 2022-12-07 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella. Nat.Struct.Mol.Biol., 29, 2022
|
|
8UPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8upn by Molmil](/molmil-images/mine/8upn) | |
7ZO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zo8 by Molmil](/molmil-images/mine/7zo8) | cryo-EM structure of CGT ABC transporter in nanodisc apo state | Descriptor: | Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, DIUNDECYL PHOSPHATIDYL CHOLINE | Authors: | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | Deposit date: | 2022-04-24 | Release date: | 2022-12-07 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ZO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zo9 by Molmil](/molmil-images/mine/7zo9) | cryo-EM structure of CGT ABC transporter in vanadate trapped state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, VANADATE ION | Authors: | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | Deposit date: | 2022-04-24 | Release date: | 2022-12-07 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella. Nat.Struct.Mol.Biol., 29, 2022
|
|
8UPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8upq by Molmil](/molmil-images/mine/8upq) | Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate. | Descriptor: | (2R)-2,3-dihydroxy-3-methylbutanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION | Authors: | Lin, X, Lonhienne, T, Guddat, L.W. | Deposit date: | 2023-10-23 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
|
|
5X42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x42 by Molmil](/molmil-images/mine/5x42) | Structure of DotL(590-659)-DotN derived from Legionella pneumophila | Descriptor: | DotN, IcmJ (DotN), IcmO (DotL), ... | Authors: | Kwak, M.J, Kim, J.D, Oh, B.H. | Deposit date: | 2017-02-09 | Release date: | 2017-06-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Architecture of the type IV coupling protein complex of Legionella pneumophila Nat Microbiol, 2, 2017
|
|
7ZNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7znu by Molmil](/molmil-images/mine/7znu) | cryo-EM structure of CGT ABC transporter in detergent micelle | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, VANADATE ION | Authors: | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | Deposit date: | 2022-04-22 | Release date: | 2022-12-07 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella. Nat.Struct.Mol.Biol., 29, 2022
|
|
7ZQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zqy by Molmil](/molmil-images/mine/7zqy) | Chaetomium thermophilum Rad50 Zn hook | Descriptor: | DH domain-containing protein, ZINC ION | Authors: | Lammens, K, Rotheneder, M, Stakyte, K. | Deposit date: | 2022-05-03 | Release date: | 2022-12-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
|
|
7ZR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zr1 by Molmil](/molmil-images/mine/7zr1) | Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | Descriptor: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | Authors: | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | Deposit date: | 2022-05-03 | Release date: | 2023-01-11 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
|
|
5IJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ijh by Molmil](/molmil-images/mine/5ijh) | |
7SH7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sh7 by Molmil](/molmil-images/mine/7sh7) | Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI87 | Descriptor: | 3C-like proteinase nsp5, benzyl [(2S,3R)-3-tert-butoxy-1-{[(2S)-3-cyclohexyl-1-oxo-1-(2-{[(3S)-2-oxopyrrolidin-3-yl]methyl}-2-propanoylhydrazinyl)propan-2-yl]amino}-1-oxobutan-2-yl]carbamate (non-preferred name) | Authors: | Blankenship, L.R, Yang, K.S, Liu, W.R. | Deposit date: | 2021-10-08 | Release date: | 2023-04-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease. Biorxiv, 2023
|
|
5EQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eqn by Molmil](/molmil-images/mine/5eqn) | Structure of phosphonate hydroxylase | Descriptor: | FrbJ, MAGNESIUM ION | Authors: | Li, C, Hu, Y, Zhang, H. | Deposit date: | 2015-11-13 | Release date: | 2016-05-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of a phosphonate hydroxylase with an access tunnel at the back of the active site. Acta Crystallogr.,Sect.F, 72, 2016
|
|
5IIQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iiq by Molmil](/molmil-images/mine/5iiq) | |
5IJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ijj by Molmil](/molmil-images/mine/5ijj) | |
5IJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ijp by Molmil](/molmil-images/mine/5ijp) | |
5XV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xv6 by Molmil](/molmil-images/mine/5xv6) | Crystal structure of ATG101-ATG13HORMA | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13 | Authors: | Kim, B.-W, Song, H.K. | Deposit date: | 2017-06-26 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.455 Å) | Cite: | The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation. Autophagy, 14, 2018
|
|
5XV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xv4 by Molmil](/molmil-images/mine/5xv4) | Crystal structure of ATG101-ATG13HORMA | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13 | Authors: | Kim, B.-W, Song, H.K. | Deposit date: | 2017-06-26 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation. Autophagy, 14, 2018
|
|
5LPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lpj by Molmil](/molmil-images/mine/5lpj) | |
5J7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5j7n by Molmil](/molmil-images/mine/5j7n) | Crystal structure of a small heat-shock protein from Xylella fastidiosa reveals a distinct high order structure | Descriptor: | Low molecular weight heat shock protein | Authors: | Fonseca, E.M.B, Scorsato, V, dos Santos, C.A, Tomazini Jr, A, Aparicio, R, Polikarpov, I. | Deposit date: | 2016-04-06 | Release date: | 2017-04-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a small heat-shock protein from Xylella fastidiosa reveals a distinct high-order structure. Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5YPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ypc by Molmil](/molmil-images/mine/5ypc) | p62/SQSTM1 ZZ domain with Phe-peptide | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-11-01 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
|
|